NCT06270459Completed
Telerehabilitation Robotics for Upper Limb Rehabilitation After STroke
Telerehabilitation Robotics for Upper Limb Rehabilitation After STroke (TRUST): a Study of Multi-cluster Adoption
Source: ClinicalTrials.gov · Last updated 2 Oct 2026
Brief summary (registry, in English)
There has been an observed decrease in motor and functional ability and non-use of the impaired limb in chronic patients. This is due to the immediate drop in intensive daily therapy (5 days per week for 3 hours/day) that is usually provided during the inpatient (acute) phase upon discharge from the hospital. In this study, the investigators plan to address the low dosage of therapy in the post-acute discharge phase for stroke survivors.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 54 (actual)
- First submitted
- 14 Feb 2024
- Start date
- 1 Nov 2024
- Primary completion date
- 6 Jan 2026
- Lead sponsor
- Tan Tock Seng Hospital
- Diseases
- Stroke
- NCT number
- NCT06270459
What you commit to
- Study type: Interventional
- Participants enrolled: 54
- From 1 Nov 2024 to the primary completion date, 6 Jan 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Non-stroke related causes of arm motor impairment.
- Medical conditions incompatible with research participation: uncontrolled medical illnesses (hypertension or diabetes, ischaemic heart disease, congestive heart failure, bronchial asthma, end stage renal/liver/heart/lung failure, unresolved cancers.
- Local factors potentially worsened by intensive robot-aided arm therapy and computer-based training: active seizures within 3 months, spasticity of Modified Ashworth Scale grades \>2 skin wounds, shoulder, arm pain VAS \> 5/10, active upper limb fractures, arthritis, fixed upper limb flexion contractures.
- History of dementia, severe depression, agitation, or behavioural problems.
Other
- Anticipated life expectancy of \< 6 months.
- Inability to tolerate sitting continuously for 60 minutes.
- Hemianesthesia of affected limb.
- Pregnancy or lactation in females
- Absence of reliable carer to provide supervision during home training
Who the study is looking for
- Clinical stroke (ischaemic or haemorrhagic) confirmed by admitting doctors and CT, CT angiography or MRI brain imaging.
- Age 21 to 90 years, both males and females.
- At least \> 28 days post stroke.
- Upper limb motor impairment of Fugl-Myer Motor Assessment (FMA) scale 10 to 60
- Has a stable home abode and a carer/ NOK to supervise home based exercise.
- Ability to sit supported continuously for 60 minutes.
- Montreal Cognitive Assessment (MOCA) score \> 21/30
- Able to understand purpose of research and give consent.
Age in the registry: 21 years to 90 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Tan Tock Seng Hospital Coordinator of this site? Confirm its status | Singapore | Singapore | Unknown status |
Related publications
- Telerehabilitation robotics for upper limb rehabilitation after stroke (TRUST): a multi-site pragmatic trial protocol.Front Neurol · 2026 · PMID 42256580
This page is information, not medical advice. Discuss any trial with your doctor.