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NCT06272240Recruiting

Tumor Microenvironment in Ovarian Cancer

Study of the Role of the Tumor Microenvironment in Ovarian Cancer

Source: ClinicalTrials.gov · Last updated 22 Feb 2024 · Not updated for over 12 months - ask the site whether it is still open

Brief summary (registry, in English)

A detailed understanding of molecular mechanism of cancer genesis is fundamental to develop innovative and personalized therapies. The new frontier in biomedical research is represented by organoids, a three-dimensional cell culture system obtained from a tissue fragment that accurately reproduces the essential properties of the original tissue in vitro, which could provide a valuable model for explanation of ovarian cancers pathogenesis and will allow to predict the response to a specific therapy. With this research project, we expect to generate ovarian cancer organoids to characterize in vitro interactions and molecular pathway among tumor cells, immune cells, and resident microbiota (intratumoral bacteria and/or microbial-derived molecules).

Status (registry)
Recruiting
Study type
Observational
Enrollment
50 (estimated)
First submitted
14 Feb 2024
Start date
2 Jan 2024
Primary completion date
Jul 2024
Lead sponsor
University of Udine
NCT number
NCT06272240

What you commit to

  • Study type: Observational
  • Planned participants: 50
  • From 2 Jan 2024 to the primary completion date, Jul 2024
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Ongoing or suspended immunosuppressive therapy within the last 6 months
  • Administration of chemotherapy for another neoplasm in the past 12 months
  • Patients not undergoing surgical intervention

Other

  • Congenital or acquired immunodeficiency
  • Immunosuppressive state
  • Non-epithelial ovarian tumors
  • BMI \> 30
  • Absence of Informed Consent

Who the study is looking for

  • Age \> 18 years
  • Age \< 80 years
  • Serous ovarian carcinoma
  • FIGO Stage III-IV

Age in the registry: 18 years to 80 years · Sex: Female · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Università degli Studi di Udine
Coordinator of this site? Confirm its status
UdineItalyRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.