NCT06272240Recruiting
Tumor Microenvironment in Ovarian Cancer
Study of the Role of the Tumor Microenvironment in Ovarian Cancer
Source: ClinicalTrials.gov · Last updated 22 Feb 2024 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
A detailed understanding of molecular mechanism of cancer genesis is fundamental to develop innovative and personalized therapies. The new frontier in biomedical research is represented by organoids, a three-dimensional cell culture system obtained from a tissue fragment that accurately reproduces the essential properties of the original tissue in vitro, which could provide a valuable model for explanation of ovarian cancers pathogenesis and will allow to predict the response to a specific therapy. With this research project, we expect to generate ovarian cancer organoids to characterize in vitro interactions and molecular pathway among tumor cells, immune cells, and resident microbiota (intratumoral bacteria and/or microbial-derived molecules).
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 50 (estimated)
- First submitted
- 14 Feb 2024
- Start date
- 2 Jan 2024
- Primary completion date
- Jul 2024
- Lead sponsor
- University of Udine
- Diseases
- Ovarian cancer
- NCT number
- NCT06272240
What you commit to
- Study type: Observational
- Planned participants: 50
- From 2 Jan 2024 to the primary completion date, Jul 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Ongoing or suspended immunosuppressive therapy within the last 6 months
- Administration of chemotherapy for another neoplasm in the past 12 months
- Patients not undergoing surgical intervention
Other
- Congenital or acquired immunodeficiency
- Immunosuppressive state
- Non-epithelial ovarian tumors
- BMI \> 30
- Absence of Informed Consent
Who the study is looking for
- Age \> 18 years
- Age \< 80 years
- Serous ovarian carcinoma
- FIGO Stage III-IV
Age in the registry: 18 years to 80 years · Sex: Female · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Università degli Studi di Udine Coordinator of this site? Confirm its status | Udine | Italy | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.