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NCT06272968Active, not recruiting

Predicting Cognition After DBS for Parkinson's Disease 2

Source: ClinicalTrials.gov · Last updated 3 Sept 2026

Brief summary (registry, in English)

The aim of the study is to improve estimation of cognitive outcome after STN-DBS in PD in order to avoid risk factors by optimizing peri- and intraoperative management and personalize therapeutic strategies for optimal long-term benefit. The investigators will test possible predictors (clinical, neuropsychological, neuroimaging, electrophysiological and molecular) for the risk of cognitive dysfunction after deep brain stimulation of the subthalamic nucleus (STN-DBS) in Parkinson's disease (PD) at a single center (Charité - Universitätsmedizin Berlin, Germany). Data collection takes place prior to as well as 3, 12 and 60 months after the STN-DBS operation. Participation is proposed to all PD patients that are planned to undergo STN-DBS after careful examination of eligibility for this treatment according to standard operation procedures.

Status (registry)
Active, not recruiting
Study type
Observational
Enrollment
30 (estimated)
First submitted
16 Feb 2024
Start date
1 Oct 2024
Primary completion date
1 Dec 2027
Lead sponsor
Charite University, Berlin, Germany
NCT number
NCT06272968

What you commit to

  • Study type: Observational
  • Planned participants: 30
  • From 1 Oct 2024 to the primary completion date, 1 Dec 2027
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • Internistic, surgical or psychiatric contrainidications with respect to the DBS operation or treatment for the STN-DBS group
  • Dementia

Other

  • Relevant language barrier

Who the study is looking for

  • Diagnosis of idiopathic Parkinson's Disease
  • Indication for STN-DBS

Age in the registry: 18 years to 80 years · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Charité Universitätsmedizin Berlin
Coordinator of this site? Confirm its status
BerlinGermanyUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.