NCT06274060Completed
Project Phakama: Testing Support Strategies to Empower Young Women on PrEP in South Africa
Optimizing PrEP Implementation and Effectiveness Among Women at High Risk for HIV Acquisition in South Africa: Phase 2b
Source: ClinicalTrials.gov · Last updated 18 Jun 2026
Brief summary (registry, in English)
The goal of this trial is to understand which strategies work best to support pre-exposure prophylaxis (PrEP) use among female sex workers (FSW) and adolescent girls and youth women (AGYW) in uMgungundlovu, KwaZulu-Natal, South Africa. Participants will be randomly assigned to receive a combination of up to four support strategies encourage the participants in continuing to use PrEP. The four strategies being tested are: case management, food vouchers, peer support buddies, and community-based PrEP pick-up points. The intention of this trial is to determine which PrEP support strategy or bundle(s) of strategies best promote(s) long-term PrEP use, so that these services can be scaled up to other districts in South Africa.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 304 (actual)
- First submitted
- 16 Feb 2024
- Start date
- 16 Apr 2024
- Primary completion date
- 1 Jun 2025
- Lead sponsor
- Johns Hopkins Bloomberg School of Public Health
- Diseases
- HIV
- NCT number
- NCT06274060
What you commit to
- Study type: Interventional
- Participants enrolled: 304
- From 16 Apr 2024 to the primary completion date, 1 Jun 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Currently on PrEP, but initiated onto PrEP more than 48 hours previously
Age
- Under 16 years of age if AGYW OR under 18 years of age if FSW
Other
- Not eligible for PrEP
Who the study is looking for
- Initiated PrEP within the past 48 hours by the TB HIV Care PrEP programme in uMgungundlovu through the female sex worker (FSW) or adolescent girls and young women (AGYW) PrEP programme teams
Age in the registry: 16 years to - · Sex: Female · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| TB HIV Care Coordinator of this site? Confirm its status | Pietermaritzburg | South Africa | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.