NCT06274593Recruiting
Study of OCT Peripapillary Angiography in Patients With Advanced Glaucoma
Source: ClinicalTrials.gov · Last updated 24 Jun 2026
Brief summary (registry, in English)
Glaucoma is a chronic disease of the optic nerve, characterized by progressive loss of nerve cells in the retina, leading to progressive loss of peripheral and central vision. There are in fact several types of glaucoma, which is the world's second leading cause of blindness after cataracts, and the leading cause of irreversible blindness. To date, to our knowledge, there is no work analyzing the progression of angiographic OCT in patients with glaucoma. The main aim of this study is to compare the 3-year progression rate of 3 examinations in advanced glaucoma patients: one functional (visual field) and two anatomical (OCTa and OCTrnfl).
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 50 (estimated)
- First submitted
- 14 Feb 2024
- Start date
- 27 Apr 2024
- Primary completion date
- 27 Apr 2027
- Lead sponsor
- Nantes University Hospital
- Diseases
- Glaucoma
- NCT number
- NCT06274593
What you commit to
- Study type: Observational
- Planned participants: 50
- From 27 Apr 2024 to the primary completion date, 27 Apr 2027
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Retinal vascular pathology (moderate to severe non-proliferative diabetic retinopathy, complicated diabetic retinopathy, OVCR/OBVR, OACR/OBAR, NOIAA...) Non-glaucomatous optic neuropathy, neurological pathology leading to visual field deficit (stroke with HLH, quadranopsia, chiasmatic Sd...)
- Retinal pathology leading to visual field impairment (e.g. retinitis pigmentosa)
- Significant environmental disorders impairing retinal imaging (e.g. active uveitis, dense cataract)
Other
- PPR (retinal PanPhotocoagulation), retinal cerclage
- AMD and other macular pathologies that can lead to central visual field deficits
- Loss of fixation point preventing visual field formation Pregnant or breast-feeding women
- Protected adults under guardianship or curatorship
- with unreliable visual fields (false positives and false negatives \> 33%)
- with an uninterpretable OCTrnfl or OCTa (artifact, low quality score)
Who the study is looking for
- Men and women aged 18 and over
- Patient with glaucoma followed in the ophthalmology department of Nantes University Hospital
- mean visual field deficit (MD) \>10dB
Age in the registry: 18 years to - · Sex: All
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Jean-Baptiste Ducloyer Coordinator of this site? Confirm its status | Nantes | France | Not yet recruiting |
| CHU Nantes Coordinator of this site? Confirm its status | Nantes | France | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.