NCT06275243Completed
Polymorphism of ApoE in Alzheimer's Disease: Genetic Study in Castile and Leon (Spain)
Alzheimer's Disease as a Sociosanitary Priority: ApoE Gene Polymorphism
Source: ClinicalTrials.gov · Last updated 8 May 2024
Brief summary (registry, in English)
The general objective of this randomized and longitudinal clinical study was to estimate the frequencies of ApoE variants both in the user population of the "Messengers of Peace" Residences and the "Associations of Relatives of Alzheimer's Patients" in Castile y Leon, since, due to its geographical location at the crossroads, it has received multiple genetic contributions from both northern Europe, the Mediterranean area and northern Africa. The main questions it aims to answer are: * What are the allelic frequencies of ApoE variants in the population of individuals with Alzheimer's disease in Castile and Leon? * Is there a correlation between the ApoE4 variant and the lipid profile in the blood of individuals with Alzheimer's disease in this region?
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 511 (actual)
- First submitted
- 30 Jan 2024
- Start date
- Jul 2022
- Primary completion date
- Mar 2023
- Lead sponsor
- Universidad de León
- Diseases
- Alzheimer disease
- NCT number
- NCT06275243
What you commit to
- Study type: Interventional
- Participants enrolled: 511
- From Jul 2022 to the primary completion date, Mar 2023
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- Subjects who, at the time of sample collection, had behavioral or other alterations that made the sample collection procedure impossible.
- Subjects who, at the time of sample collection, presented oral alterations incompatible with the technique.
Who the study is looking for
- Be between 60 and 90 years old.
- Subjects with a diagnosis of AD in the case group.
- Subjects free of AD diagnosis in the control group.
- Subjects who voluntarily and consented to participate free of charge.
- Have completed the written consent
Age in the registry: 60 years to 90 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of León Coordinator of this site? Confirm its status | León | Spain | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.