NCT06277934CompletedPhase 2
A Study of RGT001-075 in Participants With Obesity or Overweight With Weight-Related Comorbidities
A Phase 2, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study of RGT001-075 Compared With Placebo in Adult Patients With Obesity or Overweight With Weight-Related Comorbidities
Source: ClinicalTrials.gov · Last updated 7 Aug 2025
Brief summary (registry, in English)
The main purpose of this study was to evaluate the safety and tolerability of RGT001-075 in healthy participants with obesity
- Status (registry)
- Completed
- Phase (registry)
- Phase 2
- Study type
- Interventional
- Enrollment
- 73 (actual)
- First submitted
- 1 Feb 2024
- Start date
- 8 Mar 2024
- Primary completion date
- 13 Aug 2024
- Lead sponsor
- Regor Pharmaceuticals Inc.
- Diseases
- Obesity
- NCT number
- NCT06277934
What you commit to
- Study type: Interventional · Phase 2
- Participants enrolled: 73
- From 8 Mar 2024 to the primary completion date, 13 Aug 2024
- 10 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Have a prior or planned surgical treatment for obesity
- Have or plan to have endoscopic and/or device-based therapy for obesity
- Have any prior diagnosis of diabetes
Other illness
- Have obesity induced by other endocrinologic disorders or diagnosed monogenetic or syndromic forms of obesity
- Have a history of Major Depressive Disorder (MDD) or other severe psychiatric disorders within the last 2 years
- Have a history of suicide attempt.
Other
- Have an electrocardiogram (ECG) with abnormalities
Who the study is looking for
- Age ≥ 18 and ≤ 75 years
- Have a BMI ≥27 kg/m² and ≤ 45 kg/m²
- Have had a stable body weight for the 3 months prior to randomization
Age in the registry: 18 years to 75 years · Sex: All · Does not accept healthy volunteers
Sites (10)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Velocity Clinical Research Coordinator of this site? Confirm its status | Cleveland | United States | Unknown status |
| Velocity Clinical Research Coordinator of this site? Confirm its status | Dallas | United States | Unknown status |
| Velocity Clinical Research Coordinator of this site? Confirm its status | Durham | United States | Unknown status |
| Velocity Clinical Research Coordinator of this site? Confirm its status | East Greenwich | United States | Unknown status |
| Velocity Clinical Research Coordinator of this site? Confirm its status | Los Angeles | United States | Unknown status |
| Velocity Clinical Research Coordinator of this site? Confirm its status | Medford | United States | Unknown status |
| Velocity Clinical Research Coordinator of this site? Confirm its status | Omaha | United States | Unknown status |
| Velocity Clinical Research Coordinator of this site? Confirm its status | Valparaiso | United States | Unknown status |
| Velocity Clinical Research Coordinator of this site? Confirm its status | Vestal | United States | Unknown status |
| Velocity Clinical Research Coordinator of this site? Confirm its status | West Jordan | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.