NCT06278792Completed
Readily Available Urinary Sodium Analysis in Patients With Acute Decompensated Heart Failure
Source: ClinicalTrials.gov · Last updated 26 Feb 2024
Brief summary (registry, in English)
The goal of this clinical trial is to compare physician-guided (SOC) versus nurse-led natriuresis-guided diuretic therapy in patients with acute decompensated heart failure (ADHF). The main questions it aims to answer are: * difference in natriuresis and diuresis * feasibility of the protocol. Participants will be asked to gather two 24 h urine collections. Researchers will compare SOC versus nurse-led diuretic titration to see if there is a difference in natriuresis after 48 hours.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 60 (actual)
- First submitted
- 8 Feb 2024
- Start date
- 7 Mar 2022
- Primary completion date
- 12 Jul 2023
- Lead sponsor
- Ziekenhuis Oost-Limburg
- Diseases
- Heart failure
- NCT number
- NCT06278792
What you commit to
- Study type: Interventional
- Participants enrolled: 60
- From 7 Mar 2022 to the primary completion date, 12 Jul 2023
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Concomitant diagnosis of an acute coronary syndrome
- Renal replacement therapy
- Treatment with intravenous loop diuretics \> 80mg furosemide or an equivalence of another loop diuretic (40mg furosemide = 1mg bumetanide) during the index hospitalization and prior to randomization
Lab values
- Estimated GFR below 20 ml/min/1.73m\^2
Other
- Patients unable to collect a 48h-urine collection
- Need for inotropic or vasopressor support
- Ventricular assist device
Who the study is looking for
- Older than 18 years
- Provide written informed consent
- Hospital admission with signs and symptoms of congestion warranting intravenous decongestive therapy
- Congestion score of at least 2 based upon the presence of edema, pleural effusion, or ascites
- N-terminal pro-B-type natriuretic peptide (NT-proBNP) level of at least 500 ng per litre (800 ng per litre in case of atrial fibrillation)
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Ziekenhuis Oost Limburg AV Coordinator of this site? Confirm its status | Genk | Belgium | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.