NCT06280820Enrolling by invitation
Multi-Scale Analysis of Phenotypes in Heart Failure (MAP-HEART)
Multi-scale Phenotyping of Heart Failure: From Precision Phenotyping to Population Inference (PHENO-HEART)
Source: ClinicalTrials.gov · Last updated 3 Nov 2026
Brief summary (registry, in English)
Background: More than 6.5 million people in the United States live with heart failure (HF), and more than a million new cases are diagnosed each year. Treatments have improved in recent years, but researchers want to understand more about how HF develops. To do this, they need to compare blood and other samples from many people with HF. Objective: To collect blood and other samples from people with HF. These samples will be used to identify and study proteins and other factors that may lead to decreased heart function over time. Eligibility: People aged 18 years and older with heart failure. Design: Participants will be asked to join the study based on a review of their medical records. They will have 1 study visit. They will provide a blood sample: About 3 tablespoons will be collected from a needle inserted into a vein. Other tests are optional: Participants may provide urine and stool samples. They may have a cotton swab rubbed on the inside of the mouth to collect DNA. Participants may also take 3 questionnaires. They will answer questions about dietary, social, and other factors that affect their health. Participants will receive compensation. Researchers will follow the participants health by monitoring their medical records for up to 5 years.
- Status (registry)
- Enrolling by invitation
- Study type
- Observational
- Enrollment
- 2000 (estimated)
- First submitted
- 24 Feb 2024
- Start date
- 8 Nov 2026
- Primary completion date
- 30 Apr 2028
- Lead sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
- Diseases
- Heart failure
- NCT number
- NCT06280820
What you commit to
- Study type: Observational
- Planned participants: 2000
- From 8 Nov 2026 to the primary completion date, 30 Apr 2028
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- History of ventricular assist device
- History of cardiac transplant
Other
- An individual who meets any of the following criteria will be excluded from participation in this study:
- Living or residing outside of the geographic location designated for the study at the time of enrollment
Criteria the registry did not label
- INCLUSION CRITERIA:
- In order to be eligible to participate in this study, an individual must meet all of the following criteria:
- Clinical diagnosis of "active" HF documented by a cardiology provider's note in the medical record. Active HF is the presence of signs or symptoms that are deemed to be related to heart failure, as documented in the participants' medical records.
- Able and willing to undergo the consent process and provide consent
- Willing to comply with required study activities
- 18 years of age or older
Age in the registry: 18 years to 100 years · Sex: All · Does not accept healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of Maryland School of Medicine Coordinator of this site? Confirm its status | Baltimore | United States | Unknown status |
| Inova Fairfax Hospital Coordinator of this site? Confirm its status | Falls Church | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.