NCT06281041Completed
Nationwide Cohort Study of Antiplatelet Agents as Primary Prevention
Antiplatelet Agents in Patients With Intermediate Coronary Artery Stenosis and Negative Fractional Flow Reserve
Source: ClinicalTrials.gov · Last updated 14 Mar 2025
Brief summary (registry, in English)
There is no specific recommendation regarding pharmacologic treatment as primary prevention for patients with intermediate coronary artery stenosis whose revascularization was deferred based on negative fractional flow reserve (FFR). Current nationwide cohort study conducted using Korean National Health Insurance Service database evaluated the safety and efficacy of antiplatelet therapy in patients with intermediate coronary artery stenosis with deferred revascularization based on negative FFR (FFR\>0.80).
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 4657 (actual)
- First submitted
- 20 Feb 2024
- Start date
- 1 Jan 2013
- Primary completion date
- 31 Dec 2024
- Lead sponsor
- Samsung Medical Center
- Diseases
- Coronary artery disease
- NCT number
- NCT06281041
What you commit to
- Study type: Observational
- Participants enrolled: 4657
- From 1 Jan 2013 to the primary completion date, 31 Dec 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patients with previous atherosclerotic cardiovascular disease
Other illness
- Patients with history of any bleeding with blood transfusion
Other
- Patients who underween FFR measurement after expansion of reimbursement criteria of FFR (since 2021)
- Patients with use of non-vitamin K antagonist oral anticoagulants (NOAC) or warfarin
- Patients with already on antiplatelet agents including dual antiplatelet agents
Who the study is looking for
- Patients with 50-70% intermediate stenosis by quantitative coronary angiography in a vessel greater than 2.5 mm
- Patients who underwent invasive coronary angiography and FFR measurement
- Patients whose revascularization was deferred based on FFR\>0.80
Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Chonnam National University Medical School Coordinator of this site? Confirm its status | Gwangju | South Korea | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.