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NCT06282016Recruiting

Risk Factors for Neuroendocrine Neoplasms

Risk Factors for Neuroendocrine Neoplasms: a Case-control Study Based on a Record Linkage of Registry and Claims Data

Source: ClinicalTrials.gov · Last updated 7 Jan 2026

Brief summary (registry, in English)

Recent studies show an increase in neuroendocrine neoplasms, especially for the digestive tract. Previous studies suggest various risk factors that were observed for various tumor sites, e.g. a family history of cancer, tobacco and alcohol consumption as well as metabolic disorders including diabetes and obesity. A risk factor that has been little studied to date is depressive disorders, which could increase the risk of neuroendocrine neoplasms either independently or through associated risk behaviors and/or antidepressant medication. The aim of this study is to identify risk factors for neuroendocrine neoplasms based on a case-control study in order to better understand the increase of neuroendocrine neoplasms in recent decades. The study is based on a record linkage of data from the Bavarian Cancer Registry and data from the Bavarian Association of Statutory Health Insurance Accredited Physicians. While the data from the Bavarian Cancer Registry enables the identification of neuroendocrine neoplasms on the basis of histopathological findings and thus is the basis for selecting cases, the claims data from the Bavarian Association of Statutory Health Insurance Accredited Physicians provides the source population as well data on diagnoses and thus enables the investigation of risk factors.

Status (registry)
Recruiting
Study type
Observational
Enrollment
14250 (estimated)
First submitted
5 Feb 2024
Start date
15 May 2025
Primary completion date
28 Feb 2026
Lead sponsor
Bavarian Cancer Registry
NCT number
NCT06282016

What you commit to

  • Study type: Observational
  • Planned participants: 14250
  • From 15 May 2025 to the primary completion date, 28 Feb 2026
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other

  • None

Who the study is looking for

  • Persons with a statutory health insurance (about 85% of the population) and at least one outpatient physician contact in Bavaria between 2021 and 2023
  • Residence in Bavaria

Sex: All · Accepts healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Bavarian Cancer Registry, Bavarian Health and Food Safety Authority
Coordinator of this site? Confirm its status
NurembergGermanyRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.