NCT06285318Recruiting
A Study of Clinical Outcomes in Patients With Relapsed/Refractory Multiple Myeloma (RRMM) Treated With T-cell Redirectors Outside of Clinical Trials
64007957MMY4004: 64007957MMY4004 - REALiTEC
Source: ClinicalTrials.gov · Last updated 28 Aug 2026
Brief summary (registry, in English)
The purpose of this study is to describe the use of teclistamab/talquetamab in the treatment of patients with RRMM outside of clinical trials.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 900 (estimated)
- First submitted
- 27 Nov 2023
- Start date
- 18 Dec 2023
- Primary completion date
- 30 Aug 2026
- Lead sponsor
- Janssen-Cilag Ltd.
- Diseases
- Multiple myeloma
- NCT number
- NCT06285318
What you commit to
- Study type: Observational
- Planned participants: 900
- From 18 Dec 2023 to the primary completion date, 30 Aug 2026
- 68 sites in 11 countries
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- To be excluded from REALiTEC cohorts if received teclistamab as part of an interventional clinical trial
- To be excluded from REALiTAL cohort if received talquetamab as part of an interventional clinical trial
- Participants who have received teclistamab as part of a Janssen pre-approval access program are excluded from the REALiTEC Cohort 2 and REALiTEC Cohort 3
Who the study is looking for
- Have a documented diagnosis of multiple myeloma
- Received the first dose of teclistamab on or before 31 December 2022, regardless of the duration of teclistamab treatment (REALiTEC cohort 1) OR Received the first dose of teclistamab from 01 January 2023 to 31 December 2024, inclusive, regardless of the duration of teclistamab treatment (REALiTEC cohort 2) OR Received the first dose of teclistamab from 01 January 2025 to 31 December 2025, inclusive, regardless of the duration of teclistamab treatment (REALiTEC cohort 3) OR Received the first dose of talquetamab on or before 31 December 2023, regardless of the duration of talquetamab treatment (REALiTAL cohort). Participants who received both teclistamab \& talquetamab can be included in both REALiTEC and REALiTAL cohorts
- Received at least one dose of teclistamab/talquetamab
- Provision of a patient-signed informed consent form (ICF), or an ICF waiver for deceased patients as applicable based on country/site-specific requirements
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (68)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Klinikum Chemnitz gGmbH Coordinator of this site? Confirm its status | Chemnitz | Germany | Completed |
| Universitätsklinikum Carl Gustav Carus Dresden Coordinator of this site? Confirm its status | Dresden | Germany | Completed |
| University hospital Hamburg Eppendorf Coordinator of this site? Confirm its status | Hamburg | Germany | Recruiting |
| Klinikum Region Hannover Klinikum Siloah Coordinator of this site? Confirm its status | Hanover | Germany | Recruiting |
| Uniklinikum Heidelberg 1 Coordinator of this site? Confirm its status | Heidelberg | Germany | Completed |
| Klinikum Nürnberg Nord Coordinator of this site? Confirm its status | Nuremberg | Germany | Completed |
| Universitätsklinikum Würzburg Med. Klinik U. Poliklinik Ii Coordinator of this site? Confirm its status | Würzburg | Germany | Recruiting |
| Aalborg Sygehus Syd Coordinator of this site? Confirm its status | Aalborg | Denmark | Recruiting |
| Aarhus Universitetshospital Coordinator of this site? Confirm its status | Aarhus N | Denmark | Completed |
| Rigshospitalet Coordinator of this site? Confirm its status | Copenhagen | Denmark | Completed |
| Odense University Hospital Coordinator of this site? Confirm its status | Odense | Denmark | Completed |
| Sygehus Lillebælt - Vejle Coordinator of this site? Confirm its status | Vejle | Denmark | Recruiting |
| Hosp. Ntra. Sra. de Sonsoles Coordinator of this site? Confirm its status | Ávila | Spain | Recruiting |
| Hosp. Univ. Virgen de Las Nieves Coordinator of this site? Confirm its status | Granada | Spain | Recruiting |
| Hosp. Univ. de La Princesa Coordinator of this site? Confirm its status | Madrid | Spain | Recruiting |
| Hosp. Univ. de La Paz Coordinator of this site? Confirm its status | Madrid | Spain | Recruiting |
| Hosp. Costa Del Sol Coordinator of this site? Confirm its status | Málaga | Spain | Completed |
| Hosp. Clinico Univ. de Valencia Coordinator of this site? Confirm its status | Valencia | Spain | Recruiting |
| Hosp. Alvaro Cunqueiro Coordinator of this site? Confirm its status | Vigo | Spain | Recruiting |
| Hopital Albert Calmette - CHU Lille Coordinator of this site? Confirm its status | Lille | France | Recruiting |
| Institut Paoli-Calmettes Coordinator of this site? Confirm its status | Marseille | France | Completed |
| CHU de Nantes - Hôtel Dieu Coordinator of this site? Confirm its status | Nantes | France | Recruiting |
| Hopital Saint Louis Coordinator of this site? Confirm its status | Paris | France | Completed |
| Institut Universitaire du Cancer Toulouse - Oncopole Coordinator of this site? Confirm its status | Toulouse | France | Recruiting |
| CHRU de Nancy - Hopitaux de Brabois Coordinator of this site? Confirm its status | Vandœuvre-lès-Nancy | France | Completed |
| Queen Elizabeth Hospital Coordinator of this site? Confirm its status | Birmingham | United Kingdom | Recruiting |
| University College Hospital Coordinator of this site? Confirm its status | London | United Kingdom | Recruiting |
| Guys and St Thomas NHS Foundation Trust Coordinator of this site? Confirm its status | London | United Kingdom | Completed |
| The Royal Wolverhampton Hospitals NHS Trust - New Cross Hosp Coordinator of this site? Confirm its status | Wolverhampton | United Kingdom | Recruiting |
| University Hospital of Alexandroupolis Coordinator of this site? Confirm its status | Alexandroupoli | Greece | Recruiting |
| Alexandra Hospital Coordinator of this site? Confirm its status | Athens | Greece | Recruiting |
| Laiko General Hospital of Athens Coordinator of this site? Confirm its status | Athens | Greece | Recruiting |
| University Hospital of Crete, PAGNI Coordinator of this site? Confirm its status | Heraklion | Greece | Completed |
| Ioannina University Hospital Coordinator of this site? Confirm its status | Ioannina | Greece | Recruiting |
| University Hospital of Larissa Coordinator of this site? Confirm its status | Larissa | Greece | Recruiting |
| G Papanikolaou Hospital of Thessaloniki Coordinator of this site? Confirm its status | Thessaloniki | Greece | Recruiting |
| Anticancer Hospital of Thessaloniki Theageneio Coordinator of this site? Confirm its status | Thessaloniki | Greece | Recruiting |
| AHEPA University General Hospital of Thessaloniki Coordinator of this site? Confirm its status | Thessaloniki | Greece | Recruiting |
| Bon Secours Hospital Coordinator of this site? Confirm its status | Cork | Ireland | Completed |
| Cork University Hospital Coordinator of this site? Confirm its status | Cork | Ireland | Completed |
| Beacon Hospital Coordinator of this site? Confirm its status | Dublin | Ireland | Completed |
| St James Hospital Coordinator of this site? Confirm its status | Dublin | Ireland | Completed |
| University Hospital Galway - Ireland Coordinator of this site? Confirm its status | Galway | Ireland | Completed |
| Hadassah medical Center Coordinator of this site? Confirm its status | Jerusalem | Israel | Completed |
| Sheba medical center Coordinator of this site? Confirm its status | Ramat Gan | Israel | Completed |
| Tel-Aviv Sourasky Medical Center Coordinator of this site? Confirm its status | Tel Aviv | Israel | Completed |
| Policlinico Sant'Orsola-Malpighi Coordinator of this site? Confirm its status | Bologna | Italy | Completed |
| Azienda Sanitaria dell'Alto Adige - Ospedale di Bolzano Coordinator of this site? Confirm its status | Bolzano | Italy | Completed |
| Ospedale A.Perrino di Brindisi Coordinator of this site? Confirm its status | Brindisi | Italy | Completed |
| AOU Careggi Coordinator of this site? Confirm its status | Florence | Italy | Completed |
| Ospedale Vito Fazzi Coordinator of this site? Confirm its status | Lecce | Italy | Completed |
| Irccs Istituto Europeo Di Oncologia Coordinator of this site? Confirm its status | Milan | Italy | Completed |
| Policlinico di Milano Coordinator of this site? Confirm its status | Milan | Italy | Completed |
| Azienda Ospedaliera Universitaria Federico II Coordinator of this site? Confirm its status | Naples | Italy | Completed |
| Casa di Cura La Maddalena Coordinator of this site? Confirm its status | Palermo | Italy | Completed |
| Universita Cattolica del Sacro Cuore - Fondazione Policlinico Universitario 'A. Gemelli' Coordinator of this site? Confirm its status | Roma | Italy | Completed |
| Presidio Ospedaliero Santo Spirito in Sassia Coordinator of this site? Confirm its status | Roma | Italy | Completed |
| Ospedale Andrea Tortora Pagani Salerno Coordinator of this site? Confirm its status | Salerno | Italy | Completed |
| Ospedale Ca' Foncello Coordinator of this site? Confirm its status | Treviso | Italy | Completed |
| Azienda Sanitaria Universitaria Giuliano Isontina Ospedale Maggiore Coordinator of this site? Confirm its status | Trieste | Italy | Completed |
| Ospedale Castelli Coordinator of this site? Confirm its status | Verbania | Italy | Completed |
| Ospedale San Bortolo Coordinator of this site? Confirm its status | Vicenza | Italy | Completed |
| Akershus Universitetssykehus Coordinator of this site? Confirm its status | Oslo | Norway | Recruiting |
| Vestfold Hospital Trust Coordinator of this site? Confirm its status | Tønsberg | Norway | Recruiting |
| Sahlgrenska University Hospital Coordinator of this site? Confirm its status | Gothenburg | Sweden | Recruiting |
| Lanssjukhuset Ryhov Coordinator of this site? Confirm its status | Jönköping | Sweden | Completed |
| Karolinska Universitetssjukhuset Coordinator of this site? Confirm its status | Stockholms | Sweden | Recruiting |
| Uddevalla Hospital Coordinator of this site? Confirm its status | Uddevalla | Sweden | Completed |
This page is information, not medical advice. Discuss any trial with your doctor.