NCT06285461Active, not recruiting
Food Intake, Endocrine Factors and Brown Fat
Understanding the Role of Food Intake and Endocrine Factors in Brown Adipose Tissue Function
Source: ClinicalTrials.gov · Last updated 14 Apr 2026
Brief summary (registry, in English)
This study will investigate how the acute intake of foods with high and low hedonic reward differentially affects brown adipose tissue and the interplay between gut peptides, brown fat, and the brain (gut-BAT-brain axis).
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 30 (estimated)
- First submitted
- 15 Feb 2024
- Start date
- 20 Feb 2024
- Primary completion date
- 10 Mar 2026
- Lead sponsor
- Turku University Hospital
- Diseases
- Obesity
- NCT number
- NCT06285461
What you commit to
- Study type: Interventional
- Planned participants: 30
- From 20 Feb 2024 to the primary completion date, 10 Mar 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Lab values
- • Inability to have PET/CT (claustrophobia, weight \> 150 kg);
- Pregnancy and pregnancy-related conditions (postpartum/lactation during the last 12 months, or planning to become pregnant soon);
- Major alterations in the menstrual cycle (e.g., amenorrhea);
- Use of nicotine-based products;
- Hypo- or hyper- thyroidism (medical history, TSH, T3 or T4 levels out of the normal range);
- Diabetes mellitus (fasting Hb1Ac \>6.5% or fasting glycaemia\>125 mg/dL) or abnormal oral glucose tolerance test (2h OGTT \> 7.8 mmol/L);
- Hypertension (blood pressure \> 160/100 mmHg) or abnormal cardiovascular status (arrhythmia and/or long QTc in ECG, abnormal cardiac murmur, previous history of cardiovascular disease);
- Abnormal coagulopathy (e.g., clotting abnormality);
- Malignancies, immunological, autoimmune and primary/secondary immunodeficiency disorders (including or not any active treatment).
- Virus or bacterial infection (both asymptomatic and symptomatic picture) within the 30 days prior to the study start;
- Episode of fever or major surgery, burns and traumas within the month prior to the study start
- Chronic infections requiring chronic antibiotic or anti-viral treatment
- Whole blood donation in the last 3 months (\>400 mL of blood) or plans for blood donation during the entire protocol period
- Weight change (intentional or not) over the last 6-months \> than 5% of body weight, or plan to lose weight during the study,
- Use of any medication that, in the opinion of local clinician/researcher, would negatively affect or mitigate full participation and completion, or could influence the study results. This especially applies to the use of β or α adrenergic receptors agonists/antagonists (e.g., β-blockers). In addition, participants in use of medication for glucose control or weight loss such as GLP-1 analogs will not be included.
Who the study is looking for
- • Males and females
- Between 18 and 45 years old.
- For the lean group: BMI\<25.0 kg/m2
- For the group with overweight/obesity: BMI\>27.5 kg/m2 and a waist circumference of over 94 cm (men) or 80 cm (women).
Age in the registry: 18 years to 45 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Turku PET Centre Coordinator of this site? Confirm its status | Turku | Finland | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.