NCT06286696Not yet recruiting
Optic Nerve Sheath Diameter in Hypertensive Emergency
Point-of-care Ultrasound of Optic Nerve Sheath Diameter in Suspected Hypertensive Emergency
Source: ClinicalTrials.gov · Last updated 9 Oct 2024 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
This prospective observational study investigates the potential of point-of-care ultrasonography of the optic nerve sheath diameter (ONSD) to rule out papilledema in patients with suspected hypertensive emergency. The primary focus is on assessing ONSD sensitivity in identifying papilledema (hypertensive retinopathy grade 4), while secondary endpoints include hypertensive retinopathy grade 3, hypertensive encephalopathy, and the need for intravenous rapid-acting medications to lower elevated blood pressure. This study aims to determine the diagnostic characteristics of this procedure for the diagnosis of hypertensive retinopathy, thus assessing its potential as a screening tool to rule out hypertensive retinopathy by the acute internal medicine doctor.
- Status (registry)
- Not yet recruiting
- Study type
- Observational
- Enrollment
- 375 (estimated)
- First submitted
- 30 Jan 2024
- Start date
- 1 Nov 2024
- Primary completion date
- 1 Nov 2026
- Lead sponsor
- Leiden University Medical Center
- Diseases
- High blood pressure
- NCT number
- NCT06286696
What you commit to
- Study type: Observational
- Planned participants: 375
- From 1 Nov 2024 to the primary completion date, 1 Nov 2026
- No sites listed in no country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Patients with preexisting optic nerve head changes such as glaucoma, pre-existing retinal artery/vein occlusions or any other condition that makes assessment of the fundi impossible.
- Primary neurological cause of hypertension: ischemic cerebrovascular incident
Who the study is looking for
- ≥ 18 years old
- Any patient presenting to the emergency department (ED) with suspected hypertensive emergency i.e.: blood pressure of \> 200 millimetres of mercury (mmHg) systolic and/or \> 120 mmHg diastolic
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
This page is information, not medical advice. Discuss any trial with your doctor.