NCT06286761Recruiting
Routine Validation and Reproducibility Testing of Laboratory Measures and Research Techniques Used for Metabolism Research (VAL)
Routine Validation and Reproducibility Testing of Laboratory Assays and Research Techniques Used for Metabolism Research
Source: ClinicalTrials.gov · Last updated 4 Aug 2026
Brief summary (registry, in English)
The purpose of this research study is to validate (check the accuracy of) laboratory assays, intravenous catheter insertion, and equipment or devices and their reproducibility, which is necessary to perform high quality research on chronic diseases (obesity, pre-diabetes and type-2 diabetes, dyslipidemia, non-alcoholic fatty liver disease, cardiovascular disease, etc.), nutrition, and metabolism (the process by which a substance is handled in your body) at the University of Missouri. As technology changes and we start to use new testing methods, it is necessary to compare results from old tests, equipment and devices and new tests, equipment, or devices and the reproducibility of these measurements to make sure we are getting accurate results. Reproducibility means performing the same test more than once to see if the same results can be achieved each time.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 100 (estimated)
- First submitted
- 12 Feb 2024
- Start date
- 8 May 2024
- Primary completion date
- Mar 2028
- Lead sponsor
- Bettina Mittendorfer
- Diseases
- Obesity
- NCT number
- NCT06286761
What you commit to
- Study type: Observational
- Planned participants: 100
- From 8 May 2024 to the primary completion date, Mar 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- use of medications that could confound the study outcomes (e.g., anti-inflammatories, immune modulators, etc)
Other illness
- allergies or intolerances to meal ingredients, vegans or vegetarians
- alcohol use disorder as defined by the National Institute of Alcohol Abuse and Alcoholism or use of controlled substances
Age
- \<18 and \>75 years of age
- history of or current significant organ system dysfunction (e.g., heart disease, stroke, diabetes, cancer in remission for \<5 years, dementia, chronic kidney disease)
Other
- body mass index \<18.5 or \>45 kg/m2
- take dietary supplements (e.g., certain pre- and pro-biotics, fiber, fish oil supplements)
- engaged in regular structured exercise \>150 min per week
- pregnant women
- persons who use tobacco
- prisoners
- the inability to grant voluntary informed consent.
Who the study is looking for
- ≥18 and ≤75 years of age
- body mass index ≥18.5 and ≤45 kg/m2
- Weight stable (i.e., ≤3% change)
- ≤150 min of structured exercise/week for at least 2 months before entering the study
- Blood glucose: \< 126 mg/dl fasted, \< 200 mg/dl with 2 hour oral glucose tolerance testing
- Hemoglobin A1C (HbA1C) ≤6.5%
- Dyslipidemia triglycerides ≥125 mg/dL
- No chronic kidney disease
- Not vegan or vegetarian or on high protein diet (e.g. Atkins) or supplements that are not allowed
- No intolerance or allergies to study diet ingredients
- No excessive alcohol or tobacco consumption
Age in the registry: 18 years to 75 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of Missouri School of Medicine Coordinator of this site? Confirm its status | Columbia | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.