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NCT06287476Completed

Alveolar-capillary Reserve After Exercise in Chronic Obstructive Pulmonary Disease (COPD) (COP-DTPA)

Alveolar-capillary Reserve After Exercise in COPD

Source: ClinicalTrials.gov · Last updated 8 Dec 2025

Brief summary (registry, in English)

It is unknown whether individuals with COPD exhibit abnormal alveolar-capillary breaching during exercise, and whether this contributes to exertional dyspnoea. The aim of this study is to investigate whether individuals with COPD exhibit an abnormal increase in alveolar-capillary breaching during exertion, as indicated by an increase alveolar-capillary permeability with a concomitantly exacerbated increase in lung tissue mass.

Status (registry)
Completed
Study type
Interventional
Enrollment
32 (actual)
First submitted
12 Feb 2024
Start date
6 May 2024
Primary completion date
2 May 2025
Lead sponsor
Copenhagen University Hospital, Rigshospitalet
Diseases
COPD
NCT number
NCT06287476

What you commit to

  • Study type: Interventional
  • Participants enrolled: 32
  • From 6 May 2024 to the primary completion date, 2 May 2025
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Symptoms of illness, including fever, within 2 weeks prior to the study
  • Symptoms of illness, including fever, within 2 weeks prior to the study

Other illness

  • Symptoms of ischemic heart disease
  • Known heart failure
  • Known chronic lung disease
  • Symptoms of ischemic heart disease
  • Known heart failure
  • Known renal or liver disease

Other

  • Pregnancy
  • • Known renal or liver diseaseActive smoking (within 3 weeks)
  • Pregnancy
  • Active smoking (within 3 weeks)

Who the study is looking for

  • Men and women
  • 45-80 years old
  • COPD (GOLD stage I to III)
  • Resting arterial oxygenation \> 90%
  • Men and women
  • 45-80 years old
  • Non-smokers
  • Normal lung function
  • Same sex, age (± 3 years) as the COPD group

Age in the registry: 45 years to 80 years · Sex: All · Accepts healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Center For Physical Activity Research, Rigshospitalet
Coordinator of this site? Confirm its status
CopenhagenDenmarkUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.