NCT06287502Completed
Efficacy of Structured Exercise-Nutritional Intervention on Sarcopenia in Patients With Osteoporosis
Source: ClinicalTrials.gov · Last updated 23 Sept 2025
Brief summary (registry, in English)
This is a prospective parallel group, double-blinded randomized controlled trial. Subjects are randomized into two groups - the intervention group and waitlist control group. Subjects received resistance, aerobic, flexibility and balance exercise training; and nutritional supplement containing β-hydroxy β-methylbutyrate (HMB). The intervention group would first receive the intervention during the 12-week study period. Meanwhile, the waitlist control group would receive 12 weeks of conventional care. After the study period, they would receive the same intervention.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 13 (actual)
- First submitted
- 16 Feb 2024
- Start date
- 9 Sept 2022
- Primary completion date
- 30 Apr 2024
- Lead sponsor
- Kowloon Hospital, Hong Kong
- Diseases
- Osteoporosis
- NCT number
- NCT06287502
What you commit to
- Study type: Interventional
- Participants enrolled: 13
- From 9 Sept 2022 to the primary completion date, 30 Apr 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patients with metallic implants
Other illness
- Unstable medical conditions contributing to sarcopenia, for example but not limited to:
- End stage organ failure
- Unstable cardiovascular, respiratory, gastrointestinal and endocrine conditions
- Active malignancy
- Chronic kidney disease stage IV or above or with hyperkalaemia
- Diabetes mellitus on medications or with unstable control
- Terminal illness
- Self-reported allergy to the ingredients of the nutrition supplement
- Any hereditary or acquired muscular diseases
Other
- Incompetent in giving consent or following commands
- Non-ambulatory subject
- Obese subjects (BMI ≥ 25.0)
- Any orthopaedic pathologies affecting the strength of bilateral upper limbs
- Participation in other regular exercise programme
Who the study is looking for
- Diagnosis of sarcopenia:
- Low hand grip strength (Male: \<28 kg, Female: \<18 kg) AND
- Low appendicular skeletal mass by bioimpedance analysis (Male: \<7.0 kg/m2 Female: \<5.7 kg/m2)
- Diagnosed with osteoporosis by:
- Fragility fracture or
- T-score ≤-2.5 SDs at any site based upon BMD measurement by Dual Energy X-ray Absorptiometry (DXA) scan
Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Kowloon Hospital Coordinator of this site? Confirm its status | Kowloon | Hong Kong | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.