NCT06299917Active, not recruiting
WORK-ON Vocational Rehabilitation for People With Inflammatory Arthritis
WORK-ON - Vocational Rehabilitation for People With Chronic Inflammatory Arthritis - a Randomised Controlled Trial
Source: ClinicalTrials.gov · Last updated 15 Sept 2026
Brief summary (registry, in English)
People with chronic inflammatory arthritis (IA) (rheumatoid arthritis, axial spondyloarthritis, and psoriatic arthritis), often have a reduced work ability. Up to 40% lose their job in the first years after diagnosis. Consequently, they are at high risk of losing their jobs and being permanently excluded from the labour market. Therefore, a new context-specific vocational rehabilitation (VR) for people with IA was developed, based on the Medical Research Council's framework for complex interventions. The 6-months VR is called WORK-ON and consists of three parts: 1) a coordinating occupational therapist who performs an initial assessment and goalsetting process and supports cooperation between relevant partners and navigation between sectors, 2) Four group sessions with peers and if needed, 3) Individual sessions with a social worker, nurse, or physiotherapist. The objective of the WORK-ON trial is to test the overall efficacy on work ability compared to a control group who receives usual care and pamphlets for their employer and colleagues. Based on the experiences from a feasibility study, WORK-ON will be conducted as a randomised controlled trial. Patients with IA, aged 18 years or older, experiencing job insecurity will be randomised to one of two groups: the WORK-ON VR group or usual care (control group). The primary outcome; work ability measured is measured by Work Ability Index single item, at baseline, 6, 12, 18 and 30 months after baseline. Secondary outcomes are absenteeism, presenteeism, overall work impairment, activity impairment, job loss, quality of life, mental well-being, fatigue, sleep, physical activity, occupational balance and pain. Secondary outcomes are measured at baseline, 6 and 12 months after baseline. In addition, work ability, working hours per week and job loss are measured at 18 and 30 months after baseline.
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 56 (estimated)
- First submitted
- 23 Feb 2024
- Start date
- 1 Mar 2024
- Primary completion date
- 1 Aug 2028
- Lead sponsor
- The Danish Center for Expertise in Rheumatology
- NCT number
- NCT06299917
What you commit to
- Study type: Interventional
- Planned participants: 56
- From 1 Mar 2024 to the primary completion date, 1 Aug 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Major surgery was conducted within the past six months, or a surgery has been planned.
Other
- Planned or present adjustments of the pharmacological anti-rheumatic treatment (DMARDs, glucocorticoid) within the last three months.
- Presence of morbidities other than IA that may explain reduced work ability.
- Is under examination for comorbidities that influence work ability.
- Is unable to understand or speak Danish at a sufficient level to participate.
- Has cognitive or psychological impairments that may affect participation.
- Planned or ongoing participation in another rehabilitation program (apart from physiotherapy).
- Has participated in the WORK-ON feasibility study.
- Retirement application process is ongoing or plans to retire within the next five years.
- Has taken long-term sick leave (\>4 weeks).
Who the study is looking for
- Aged 18-65 years.
- Diagnosed with RA, PsA or axSpA by a rheumatologist.
- Undertakes paid work (full- or part-time work or studying).
- Able to read and understand Danish.
- Answers 'unlikely' or 'not certain' to question #6 from the WAI questionnaire: 'Do you believe, according to your present state of health, that you will be able to do your current job two years from now?' (36).
- Willing to participate in an RCT of the modified WORK-ON VR.
Age in the registry: 18 years to 65 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Danish Hospital for Rheumatic Diseases Coordinator of this site? Confirm its status | Sønderborg | Denmark | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.