NCT06304285Recruiting
A Study Assessing the Effects of Acupuncture in Parkinson's Disease Patients With Chronic Appendicitis
A Study Assessing the Effects of Acupuncture in Parkinson's Disease Patients With Chronic Appendicitis: a Single-center, Randomized, Double-blind Study
Source: ClinicalTrials.gov · Last updated 12 Mar 2024 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
The incidence of PD is high, and when the disease is serious to a certain extent, the effect of drugs to control symptoms decreases, resulting in a significant reduction in the quality of life of patients. Recent studies have found that these PD symptoms are closely related to the intestine. For several cases of PD syndrome patients complicated with chronic appendicitis, our research group conducted acupuncture on points related to constipation and chronic appendicitis, and found that constipation and related motor symptoms of patients could be significantly improved. Clinical studies have shown that acupuncture also has a certain therapeutic effect on non-motor symptoms of Parkinson's disease, such as anxiety and depression, decreased olfactory function, sleep disorders, constipation, early skeletal muscle pain, cognitive dysfunction, etc., which can delay the progression of the disease and improve the quality of life of patients. Starting from intestinal acupuncture, this project further clarified the role of acupuncture treatment in the comprehensive treatment of PD
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 84 (estimated)
- First submitted
- 27 Feb 2024
- Start date
- 1 Mar 2024
- Primary completion date
- 31 Dec 2026
- Lead sponsor
- The First Affiliated Hospital of University of Science and Technology of China
- Diseases
- Parkinson disease
- NCT number
- NCT06304285
What you commit to
- Study type: Interventional
- Planned participants: 84
- From 1 Mar 2024 to the primary completion date, 31 Dec 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Treatment with dopamine blockers or dopamine depleters in doses and time courses consistent with drug-induced parkinsonism.
- Patients who had suffered severe brain trauma or underwent complex craniotomy within 5 years prior to enrollment.
Other illness
- Cognitive disorders that are not on the Parkinson's spectrum, such as Alzheimer's disease, frontotemporal dementia, and Niemann-Pick disease, have been diagnosed.
- People diagnosed with severe neuropsychiatric disorders (epilepsy, bipolar disorder, major depressive episode, etc.) according to DSM-V.
- Complicated with serious systemic diseases, disorders of consciousness, stroke, serious coronary heart disease, diabetes, liver and kidney diseases, and serious visual and hearing disorders.
Other
- Neuroimaging examination of presynaptic dopaminergic system function was normal.
- Patients with severe organic or functional dysphagia;Those who were deemed by the researcher to be unable to complete the visit and auxiliary examination as required by the study protocol.
Who the study is looking for
- Patients presenting with bradykinesia, combined with resting tremor and/or myotonia.
- Appendix CT suggested chronic appendicitis evaluated by two experienced experts.
- All subjects and their guardians give informed consent to the content of this study and sign informed consent.
- Normal coagulation function.
- If the patient had taken oral anti-PD drugs, it had been stable for at least 2 weeks at enrollment.
Age in the registry: 40 years to 70 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| The First Affiliated Hospital of University of Science and Technology of China Coordinator of this site? Confirm its status | Hefei | China | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.