NCT06304389Recruiting
Effect of Blue Light on Vagus Nerve Stimulation in Patients With Refractory Epilepsy
Source: ClinicalTrials.gov · Last updated 2 Nov 2026
Brief summary (registry, in English)
Vagus nerve stimulation (VNS) is an adjunctive treatment for refractory epilepsy. Although widely used, there is still a substantial number of patients with insufficient response. Light, and particularly blue light, can stimulate alertness, attention and cognition through modulation of anatomical targets which are common to the vagal afferent network. This project aims at understanding how exposure to blue enriched light may influence VNS effects in patients with refractory epilepsy by exploring the modulation of a series of biomarkers of VNS action. This could possibly lead to new therapeutic strategies to increase efficacy of VNS.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 34 (estimated)
- First submitted
- 18 Apr 2023
- Start date
- 1 Jul 2023
- Primary completion date
- 1 Jul 2023
- Lead sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
- Diseases
- Epilepsy
- NCT number
- NCT06304389
What you commit to
- Study type: Interventional
- Planned participants: 34
- From 1 Jul 2023 to the primary completion date, 1 Jul 2023
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- other medical implanted devices than VNS, ocular diseases
- medical implanted devices, cerebral trauma, ocular disease
Other
- Patients:
- Helthy participants:
Who the study is looking for
- Patients:
- VNS implanted since at least 3 months age \>18-60 years; IQ \>55 on Wechsler scale (normal status or mild cognitive impairment)
- healthy participants aged between 18 and 35 years without any medical history (neurological / psychiatric disease)
Age in the registry: 18 years to 60 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Cliniques universitaires Saint-Luc Coordinator of this site? Confirm its status | Woluwe-Saint-Lambert | Belgium | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.