NCT06307327Recruiting
Comparative Study of New Classification and Traditional Classification of Radioactive Oropharyngeal Mucositis
A Comparative Study on the Evaluation Consistency Between the New Type and the Traditional Grade of Radioactive Oropharyngeal Mucositis and the Exploration of Blood Markers
Source: ClinicalTrials.gov · Last updated 16 Jul 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
Radiation oropharyngeal mucositis is one of the most painful side effects of radiotherapy in patients with head and neck tumors. However, the traditional radioactive oropharyngeal mucositis grading system has the problem of poor evaluation consistency. To solve this problem, we innovatively classify radiation oropharyngeal mucositis into four types according to the four-stage histopathological changes of acute radiation injury: (1) congestive; (2) Scattered erosion type; (3) Fusion erosion type; (4) Ulcer type. We intend to conduct a multicenter observational cohort study to compare the consistency of different physicians in the assessment of radiation oropharyngeal mucositis with new and traditional classifications, and to explore changes in blood markers of different types of oropharyngeal mucositis using clinical residual blood samples.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 264 (estimated)
- First submitted
- 6 Mar 2024
- Start date
- Sept 2025
- Primary completion date
- Jun 2026
- Lead sponsor
- Nanfang Hospital, Southern Medical University
- Diseases
- Head and neck cancer
- NCT number
- NCT06307327
What you commit to
- Study type: Observational
- Planned participants: 264
- From Sept 2025 to the primary completion date, Jun 2026
- 4 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Lab values
- They also have other uncontrolled serious medical conditions, such as unstable heart disease requiring treatment, poorly controlled diabetes (fasting blood glucose \> 1.5× the upper limit of normal), mental illness, and a history of severe allergies
Who the study is looking for
- Voluntarily sign informed consent;
- Age 18 or older on the date of signing the informed consent;
- Histologically confirmed head and neck tumor, radiotherapy or chemoradiotherapy.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (4)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Southern Medical University Coordinator of this site? Confirm its status | Guangzhou | China | Recruiting |
| Huizhou Central People's Hospital Coordinator of this site? Confirm its status | Huizhou | China | Not yet recruiting |
| Jieyang People's Hospital Coordinator of this site? Confirm its status | Jieyang | China | Not yet recruiting |
| Meizhou People's Hospital, Meizhou Academy of Medical Sciences Meizhou Coordinator of this site? Confirm its status | Meizhou | China | Not yet recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.