NCT06312046Recruiting
Motor-cognitive Performance in People With Multiple Sclerosis
Motor-cognitive Performance in People With Multiple Sclerosis - Brain Activity and Effects of Balance Exercise
Source: ClinicalTrials.gov · Last updated 10 Jul 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
Having a neurological disease such as multiple sclerosis (MS) leads to difficulties in balance and gait with or without concurrent performance of cognitive tasks, hindering activity performance and influencing the possibilities for an independent lifestyle. The investigators have adapted a previously developed balance training program to a highly challenging program specifically directed to MS (HiBalance-MS). This program was recently tested and found feasible in a pilot study. The investigators will now perform a randomized controlled trial in people with MS, in order to determine the effects of the program. The hypothesis is that progressively challenging balance exercise programs that are specific to the balance control domains affected by MS will be effective to improve balance control, walking, motor-cognitive performance, activity performance and health related quality of life.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 90 (estimated)
- First submitted
- 4 Mar 2024
- Start date
- 26 Feb 2024
- Primary completion date
- 31 Dec 2025
- Lead sponsor
- Karolinska Institutet
- Diseases
- Multiple sclerosis
- NCT number
- NCT06312046
What you commit to
- Study type: Interventional
- Planned participants: 90
- From 26 Feb 2024 to the primary completion date, 31 Dec 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- cognitive impairment as indicated by a score \<21 in the Montreal Cognitive Assessment;
- presence of other conditions that would substantially influence balance;
- an MS relapse or change of disease-modifying treatment within the past 8 weeks
Who the study is looking for
- an MS diagnosis according to McDonald criteria;
- an overall MS-disability score from 2.0 to 5.5 according to the Expanded Disability Status Scale;
- ability to walk 100 m without aid;
- a maximum score of 24 in the Mini-BESTest (i.e., \< 25 points)
- 18 to 65 years of age
Age in the registry: 18 years to 65 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Karolinska Institutet Coordinator of this site? Confirm its status | Stockholm | Sweden | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.