NCT06314958Recruiting
Stage II/III Colorectal Cancer Recurrence
Predicting Recurrence-Free Survival in Stage III and High-Risk Stage II Colorectal Cancer After Curative-Intent Treatment
Source: ClinicalTrials.gov · Last updated 7 Jul 2026
Brief summary (registry, in English)
This study will develop an assay to predict disease recurrence in patients with stage II/III CRC after receiving adjuvant chemotherapy, using genome-wide DNA methylation.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 400 (estimated)
- First submitted
- 11 Mar 2024
- Start date
- 15 Mar 2023
- Primary completion date
- 18 Jun 2028
- Lead sponsor
- City of Hope Medical Center
- Diseases
- Colorectal cancer
- NCT number
- NCT06314958
What you commit to
- Study type: Observational
- Planned participants: 400
- From 15 Mar 2023 to the primary completion date, 18 Jun 2028
- 4 sites in 3 countries
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Development of recurrence in the first 6 months following adjuvant chemotherapy completion.
Other illness
- Hereditary colorectal cancer syndromes (identified through genetic testing)
- Inflammatory bowel diseases
Other
- Lack of written informed consent.
Who the study is looking for
- Stage II (high-risk) or III colorectal cancer (TNM classification, 8th edition).
- Received standard diagnostic, staging, and therapeutic procedures as per local guidelines
- Received stage-specific curative-intent resection followed by adjuvant chemotherapy.
- Confirmed cancer-free survivorship confirmed at the time of study inclusion.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (4)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Second Affiliated Hospital of Dalian Medical University Coordinator of this site? Confirm its status | Dalian | China | Recruiting |
| Barcelona University Coordinator of this site? Confirm its status | Barcelona | Spain | Recruiting |
| La Paz University Hospital Coordinator of this site? Confirm its status | Madrid | Spain | Recruiting |
| City of Hope Medical Center Coordinator of this site? Confirm its status | Monrovia | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.