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NCT06320392Completed

Implication of CCR4-NOT Complex Subunit 7 Expression in Natural Killer Cell Resistance in Metastatic Breast Cancer

CNOT7 Blood Level and Correlation to LAIR-1 in Metastatic vs Non-metastatic Breast Cancer Egyptian Patient's Cohort; a Case-Controlled Mechanistic Study

Source: ClinicalTrials.gov · Last updated 31 Jul 2024

Brief summary (registry, in English)

Being a mechanistic study, this work aims to figure out "the role of the cytoplasmic mRNA deadenylase CNOT7 expressed protein on NK cell resistance in metastatic BC". In other words, to explore, whether, "CNOT7 contributes to metastasis in Egyptian female metastatic BC patient's cohort, through NK cell resistance, or not."

Status (registry)
Completed
Study type
Observational
Enrollment
90 (actual)
First submitted
23 Feb 2024
Start date
1 Jul 2021
Primary completion date
1 May 2023
Lead sponsor
Ain Shams University
NCT number
NCT06320392

What you commit to

  • Study type: Observational
  • Participants enrolled: 90
  • From 1 Jul 2021 to the primary completion date, 1 May 2023
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • breast cancer patients with blood disorders
  • breast cancer patients with any cancer other than BC
  • breast cancer patients with liver cirrhosis
  • breast cancer patients with uterine or urinary bladder diseases
  • breast cancer patients with incomplete data or incomplete histopathology diagnosis report

Who the study is looking for

  • Adults over 18 years old with breast carcinoma of no special type (NST) confirmed pathologically.

Sex: Female · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Faculty of Pharmacy, Ain Shams University, Advanced Biochemistry Research Lab
Coordinator of this site? Confirm its status
CairoEgyptUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.