NCT06322355Completed
Comparison of UFR With QFR in Stable Coronary Artery Disease
Comparison of Flow Ratio Derived From Intravascular Ultrasound With Coronary Angiography in Stable Coronary Artery Disease: Correlation With Fractional Flow Reserve
Source: ClinicalTrials.gov · Last updated 21 Mar 2024
Brief summary (registry, in English)
Quantitative flow reserve (QFR), derived from coronary angiography, has shown high accuracy in detecting significant lesions. Ultrasonic flow ratio (UFR), a new development from IVUS, integrates physiological estimation with intravascular imaging. Although both QFR and UFR are effective, there's no conclusive evidence favoring one over the other. The study aims to compare UFR and QFR's diagnostic performance against the conventional FFR standard in detecting significant coronary lesions.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 250 (actual)
- First submitted
- 15 Jan 2024
- Start date
- 1 Jul 2018
- Primary completion date
- 31 Dec 2023
- Lead sponsor
- Shanghai Zhongshan Hospital
- Diseases
- Coronary artery disease
- NCT number
- NCT06322355
What you commit to
- Study type: Observational
- Participants enrolled: 250
- From 1 Jul 2018 to the primary completion date, 31 Dec 2023
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- The use of balloon predilatation or stent placement prior to FFR measurement or IVUS imaging
- History of previous coronary artery bypass grafting,
Other illness
- The presence of a severe myocardial bridge (defined as ≥30% systolic diameter stenosis) in the examined vessel
Lab values
- Left ventricular ejection fraction \<35%
Other
- Inadequate quality of CAG or IVUS images for QFR or UFR calculation
- Left main or ostial right coronary artery lesion
- Incomplete IVUS pullback across the entire lesion segment
Who the study is looking for
- Patients who underwent both IVUS imaging and FFR measurement on the same artery
Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Zhongshan Hospital,Fudan University Coordinator of this site? Confirm its status | Shanghai | China | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.