NCT06323421Completed
Targeting Chronic Stress for Reducing Risk Factors for Colorectal Cancer
Mindfulness and CRC Risk Factor Reduction: Targeting Chronic Stress For Colorectal Cancer Risk Factor Reduction A Pilot Feasibility Study Among Vulnerable At-Risk Black Females
Source: ClinicalTrials.gov · Last updated 27 Oct 2026
Brief summary (registry, in English)
Many neighborhoods in Chicago experience daily exposure to stressors including economic inopportunity and violent crime in public spaces. There is mounting evidence that chronic psychosocial stress can facilitate carcinogenesis by modulating the gut microbiome and immune system. The proposed research aims to study the practice of mindfulness to mitigate CPS and reduce colorectal cancer risk factors among Black American women at elevated risk.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 24 (actual)
- First submitted
- 1 Mar 2024
- Start date
- 15 Jul 2024
- Primary completion date
- 10 Jul 2025
- Lead sponsor
- University of Illinois Chicago
- Diseases
- Colorectal cancer
- NCT number
- NCT06323421
What you commit to
- Study type: Interventional
- Participants enrolled: 24
- From 15 Jul 2024 to the primary completion date, 10 Jul 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Bariatric surgery or bowel resection
Other illness
- History of CRC
- Inflammatory bowel disease or genetic predisposition to CRC
- Cancer diagnosis or cancer treatment in the past 12 months
- Immunodeficiency/autoimmune disease
- Significant health conditions or take medications that impact participation or expected outcomes (e.g., β-blocker, Cushing's syndrome, and corticosteroids - inhaled, topical, oral in the past month given effects on hair cortisol measurement)
Lab values
- Uncontrolled diabetes (HbA1c \> 9% based on EHR)
Other
- Antibiotics (oral/IV) in the past 2 months
- Consume \> 50 grams of ethanol daily
- Use combustible tobacco
- Fiber or pre-/probiotic supplements \> 3 days per week
- Serrated adenoma at the recent colonoscopy given the molecular features are distinct
Who the study is looking for
- Female based on sex assigned at birth
- Self-identify as Black
- Age 45-65 years old
- Completed a colonoscopy in the past 24 months,
- Classify as elevated risk of CRC defined as: any colorectal adenoma detected in past 24 months
- Own and use a smartphone, computer, or tablet with access to the Internet
- Score ≥ 14 on the PSS at screening
- Reside in a Chicago community with high violent crime
Age in the registry: 45 years to 65 years · Sex: Female · Accepts healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of Illinois Chicago Coordinator of this site? Confirm its status | Chicago | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.