NCT06332131Active, not recruiting
Effects of Immune Checkpoint Inhibitors on Coronary Microvasculature
Source: ClinicalTrials.gov · Last updated 5 Oct 2026
Brief summary (registry, in English)
This is an observational study that includes patients with breast cancer or non-small cell lung cancer who will be treated with immune checkpoint inhibitor (ICI) therapy. The investigators will use echocardiograms, blood draws, and PET stress tests to understand how ICI therapy affects the heart and circulatory system.
- Status (registry)
- Active, not recruiting
- Study type
- Observational
- Enrollment
- 25 (estimated)
- First submitted
- 20 Mar 2024
- Start date
- 15 Jan 2025
- Primary completion date
- 30 Nov 2026
- Lead sponsor
- Abramson Cancer Center at Penn Medicine
- Diseases
- Lung cancer
- NCT number
- NCT06332131
What you commit to
- Study type: Observational
- Planned participants: 25
- From 15 Jan 2025 to the primary completion date, 30 Nov 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Prior treatment with ICI therapy.
Other
- Pregnant or breast-feeding:
- Vulnerable patients, including pregnant women and prisoners
- Absolute Contraindication to rest/vasodilator stress PET/CT
Who the study is looking for
- ≥18 years of age
- Either diagnosis of breast cancer with plan for treatment according to the Keynote 522 regimen or non-small-cell lung cancer planned for neoadjuvant treatment that includes pembrolizumab
- Able to provide written informed consent
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Abramson Cancer Center at University of Pennsylvania Coordinator of this site? Confirm its status | Philadelphia | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.