NCT06333236Completed
Effect of Kron (Citicoline and Nicotinamide Oral Solution) on Patients With Open-angle Glaucoma
Source: ClinicalTrials.gov · Last updated 22 Sept 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
Aim of this study is to investigate the administration effects of the combination of citicoline 40mg/ml and nicotinamide 15mg/ml oral solution (Kron®) on short term improvement in inner retinal function, bioelectrical activity of the visual cortex and visual function.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 30 (actual)
- First submitted
- 1 Feb 2024
- Start date
- 10 Apr 2025
- Primary completion date
- 15 Jul 2025
- Lead sponsor
- ASST Santi Paolo e Carlo
- Diseases
- Glaucoma
- NCT number
- NCT06333236
What you commit to
- Study type: Interventional
- Participants enrolled: 30
- From 10 Apr 2025 to the primary completion date, 15 Jul 2025
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- ophthalmic surgery 6 months before the recruitment
- treatment with supplements in any form with a demonstrated or presumed neuroprotecting/neuroenhancing effect in the last six months
Other illness
- presence of cataract or other conditions that could affect results of perimetry or electroretinography
- presence of other ocular or systemic diseases that could affect results of perimetry or electroretinography.
Other
- angle closure glaucoma and secondary open angle glaucoma
- refractive error outside +2D and -6D
Who the study is looking for
- glaucomatous patients with moderate visual field loss, MD ranging from -6 dB and -12 dB, and risk of progression
- controlled intraocular pressure
- at least 3 previous visual field examinations.
Age in the registry: 40 years to 70 years · Sex: All · Does not accept healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Luca Rossetti Coordinator of this site? Confirm its status | Milan | Italy | Unknown status |
| Asst Santi Paolo E Carlo Coordinator of this site? Confirm its status | Milan | Italy | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.