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NCT06333652RecruitingPhase 2

Ravulizumab in Pregnancies Complicated by Severe Hypertensive Disorders

Clinical Trial on the Use of Ravulizumab in Pregnancies Complicated by Severe Hypertensive Disorders

Source: ClinicalTrials.gov · Last updated 22 Oct 2026

Brief summary (registry, in English)

The researchers are testing a medication named ravulizumab for the treatment of severe preeclampsia and Hemolysis, Elevated Liver enzymes, Low Platelets (HELLP) syndrome.

Status (registry)
Recruiting
Phase (registry)
Phase 2
Study type
Interventional
Enrollment
14 (estimated)
First submitted
20 Mar 2024
Start date
Apr 2027
Primary completion date
Dec 2028
Lead sponsor
Mayo Clinic
NCT number
NCT06333652

What you commit to

  • Study type: Interventional · Phase 2
  • Planned participants: 14
  • From Apr 2027 to the primary completion date, Dec 2028
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • Individuals with non-reassuring fetal status requiring delivery, non-viable fetuses, previable pregnancy (\<23 0/7 weeks gestation), stroke, in utero fetal demise, known atypical hemolytic uremic syndrome, familial or acquired thrombocytopenia purpura, paroxysmal nocturnal hemoglobinuria, allergy to Ravulizumab, inability or unwillingness to sign informed consent.

Other

  • Pregnant female patients presenting with disseminated intravascular coagulopathy (DIC).

Who the study is looking for

  • Individuals with \< 34 0/7 weeks of gestation.
  • Individuals with severe preeclampsia or HELLP features.

Age in the registry: 18 years to 50 years · Sex: Female · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Mayo Clinic Minnesota
Coordinator of this site? Confirm its status
RochesterUnited StatesRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.