NCT06341439Completed
Clinical Efficacy of Mouthrinses Based on Chlorhexidine 0.12% and CITROX®
Clinical Efficacy of Mouthrinses Based on Chlorhexidine 0.12% and CITROX® as a Support to Non-surgical Periodontal Therapy: a Randomized Controlled Triple-blind Clinical Trial
Source: ClinicalTrials.gov · Last updated 21 Mar 2025
Brief summary (registry, in English)
The goal of the following clinical trial is to compare the efficacy of a product based on chlorhexidine 0.12% and CITROX and the same product without CITROX in the healing phenomena that occur after non-surgical periodontal therapy. The main questions it aims to answer are: * Is the response to periodontal therapy better if mouthwashes containing bioflavonoids are used as a support to non surgical periodontal therapy? * What is the patients' perception? Participants, divided into 2 groups, are asked to use either one or the other mouthwash for 14 days after non-surgical periodontal therapy.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 40 (actual)
- First submitted
- 14 Mar 2024
- Start date
- 1 Apr 2024
- Primary completion date
- 1 Jun 2024
- Lead sponsor
- University of L'Aquila
- NCT number
- NCT06341439
What you commit to
- Study type: Interventional
- Participants enrolled: 40
- From 1 Apr 2024 to the primary completion date, 1 Jun 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Radiotherapy in the head and neck region;
- Taking drugs that cause alterations in the gums and oral mucosa;
- Periodontal treatment in the previous 6 months.
Other illness
- Uncontrolled diabetes or hypertension;
- Documented allergy to chlorhexidine or hyaluronic acid;
Other
- Severe general medical pathologies;
- Immunodeficiency states;
- Smokers \>5 cigs/day;
- Impossibility to carry out homogeneous and continuous follow-up;
- Pregnancy or breastfeeding;
- Presence of removable prostheses;
Who the study is looking for
- ASA I and ASA II patients;
- Age \> 21 years;
- Non-smokers or smokers \< 5 cig/day;
- Presence of periodontal disease;
- \>10 natural teeth;
- At least 2 teeth with pockets ≥5mm;
- Indications for carrying out at least one SRP (scaling and root planing) session;
- Signing of the written informed consent to participate in the study.
Age in the registry: 21 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of L'Aquila, division of periodontology Coordinator of this site? Confirm its status | L’Aquila | Italy | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.