NCT06341829Enrolling by invitation
Visuospatial and Affective Abilities in Parkinson Disease
Assessment and Rehabilitation of Visuospatial and Affective Abilities in Parkinson Disease
Source: ClinicalTrials.gov · Last updated 24 Feb 2026
Brief summary (registry, in English)
The aim of the study is to investigate whether prismatic adaptation (PA) and virtual prismatic adaptation (VPA), a non-invasive neuromodulation technique, that involves the use of lenses that deviate the visual field, can modulate alexithyima and performance in visuospatial tasks in patients with Parkinson disease. Furthermore, brain activity during the prismatic adaptation and post-adaptation phases will be recorded using functional near-infrared spectroscopy (fNIRS) and high-density electroencephalography (HD-EEG). Based on these premises, the present project aims to investigate the deficits of the affective, motor and visuospatial abilities in Parkinson's patients and the modulation of disorders through prismatic adaptation (PA) and virtual prism adaptation (VPA). Finally, we would like to evaluate production of the tear film and correlate their quantity with the severity of PD as it could be proposed as a new, non-invasive biomarker.
- Status (registry)
- Enrolling by invitation
- Study type
- Interventional
- Enrollment
- 126 (estimated)
- First submitted
- 8 Mar 2024
- Start date
- 30 Apr 2024
- Primary completion date
- 1 May 2024
- Lead sponsor
- IRCCS Centro Neurolesi Bonino Pulejo
- Diseases
- Parkinson disease
- NCT number
- NCT06341829
What you commit to
- Study type: Interventional
- Planned participants: 126
- From 30 Apr 2024 to the primary completion date, 1 May 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Visual system disorders (blindness, glaucoma);
- PD with dementia according to the criteria of the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV) (American Psychiatric Association).
Other
- \- Sensory-motor deficits that can hinder neuropsychological assessment;
- Atypical parkinsonisms;
Who the study is looking for
- Over 18 years old;
- Right-handed;
- Diagnosis of idiopathic Parkinson's disease according to the UK Brain Bank criteria (Lyon and Pahwa, 2011);
- Hoehn and Yahr Stadium (Hoehn and Yahr, 1996) \<2,5;
- Stable pharmacological treatment (dopaminergic therapy: dopamine agonists and Levo-dopa) in the last 6 weeks.
Age in the registry: 18 years to 90 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Laura Culicetto Coordinator of this site? Confirm its status | Messina | Italy | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.