NCT06347146Active, not recruiting
Bridges2Scale: Testing Implementation Strategies
Bridges2Scale: Testing Implementation Strategies for an Economic Empowerment Intervention Among Young People Orphaned by AIDS
Source: ClinicalTrials.gov · Last updated 29 May 2026
Brief summary (registry, in English)
The goal of this clinical trial is to compare two multifaceted strategies (standard vs enhanced) for scaling Bridges in a two-arm Hybrid III effectiveness-implementation cluster randomized controlled trial (RCT) in adolescent and youths affected by AIDS \[AYaAIDS\] (ages 11-17 years) from 48 schools in the Greater Masaka region of Uganda. The main aims of the clinical trial are: Aim 1. Compare the implementation effectiveness of the standard implementation strategy vs. an enhanced implementation strategy. The investigators will assess fidelity to Bridges (primary implementation outcome) and sustainment of Bridges (exploratory implementation outcome). Aim 2. Determine the clinical effectiveness of Bridges implemented via a standard vs. enhanced implementation strategy. Aim 3: Explore implementation processes, mechanisms, and determinants. Aim 4. Compare the cost and cost-effectiveness of the two implementation strategies. Using an activity-based ingredients approach, the investigators will examine how much each strategy costs to achieve a unit of effect.
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 1440 (actual)
- First submitted
- 17 Mar 2024
- Start date
- 4 Jun 2024
- Primary completion date
- 31 Mar 2028
- Lead sponsor
- Washington University School of Medicine
- Diseases
- HIV
- NCT number
- NCT06347146
What you commit to
- Study type: Interventional
- Participants enrolled: 1440
- From 4 Jun 2024 to the primary completion date, 31 Mar 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- 1\. anyone with a significant cognitive impairment that interferes with their understanding of the informed consent process, or is unable/unwilling to consent.
Who the study is looking for
- Adolescent inclusion criteria:
- Ages 11-17
- a student at one of the 48 public primary schools included in the study-schools located in high HIV/AIDS prevalence areas in the greater Masaka region
- living within a family and not an institution/orphanage
- Caregiver inclusion criteria:
- self-identified and confirmed by the adolescent and youth as primary caregiver of the adolescent and youth
- capable of providing informed consent
- Youth-serving NGOs inclusion criteria:
- registered with the government of Uganda
- willing to work with the study team
- have a history of implementing micro-finance economic empowerment interventions.
Age in the registry: 11 years to 17 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| International Center for Child Health and Development Coordinator of this site? Confirm its status | Masaka | Uganda | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.