NCT06348771Completed
Postprandial Inflammation and Nuts (PIN) in Older Adults
Postprandial Inflammation and Peanuts in Older Adults
Source: ClinicalTrials.gov · Last updated 13 May 2026
Brief summary (registry, in English)
The aging population is rapidly increasing, and it is important to identify dietary factors that can prevent disease and promote health in this group. Legumes, such as peanuts, are a plant-based food high in protein and unsaturated fat making this a healthy choice, but are not consumed frequently enough in older adults. Studies have shown that regular nut consumption is associated with lower adiposity and reduced weight gain and inflammation. Given these findings, this study will examine the postprandial effects of meals with 2 levels of saturated fatty acids (SFA) on metabolic endotoxemia, inflammation and satiety, using a randomized cross-over design. The low SFA meal includes peanuts that are high in monounsaturated fatty acids (MUFA) and this will be compared to a high SFA meal. The results of this study have the potential to provide valuable insights into the role of peanuts in promoting health and preventing disease in at-risk older adults.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 17 (actual)
- First submitted
- 22 Mar 2024
- Start date
- 25 Mar 2024
- Primary completion date
- 6 Jan 2025
- Lead sponsor
- Rutgers, The State University of New Jersey
- Diseases
- Obesity
- NCT number
- NCT06348771
What you commit to
- Study type: Interventional
- Participants enrolled: 17
- From 25 Mar 2024 to the primary completion date, 6 Jan 2025
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Any surgery in the past 6 months
- Currently using or have used antibiotics continuously \> 3 days in the past 3 months
- Recent colonoscopy (within the previous two months)
Other illness
- Diagnosed with, active, or history of liver cirrhosis, chronic or persisting hepatitis
- Diagnosed with, active, or history of cancer
- History of gastrointestinal disease or surgical procedure for weight loss.
- Diagnosed with immune diseases, type 1 or 2 diabetes, pancreatitis, metabolic bone disease or infectious diseases
- Regular use of medications for that affect the gastrointestinal tract, cholecystitis, urinary tract infection, significant renal disease, severe organic diseases including coronary heart disease, myocardial infarction, infectious diseases including pulmonary tuberculosis and AIDS
- Known allergy or intolerance to any ingredients in the meal intervention
- Uncontrolled hypertension or uncontrolled severe hyperlipidemia.
Other
- Anemia
- Participation in another clinical research trial that may interfere with the results of this study.
Who the study is looking for
- Older adults across all racial/ethnic groups
- Older men, and postmenopausal women \> 2 years since last menses.
Age in the registry: 55 years to - · Sex: All · Accepts healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Foran Hall Coordinator of this site? Confirm its status | New Brunswick | United States | Unknown status |
| Rutgers University - NJ Inst Food Nutrition & Health Coordinator of this site? Confirm its status | New Brunswick | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.