NCT06352632RecruitingPhase 3
ACT-GLOBAL Adaptive Platform Trial for Stroke
A Multi-faCtorial, mulTi-arm, Multi-staGe, Randomised, gLOBal Adaptive pLatform Trial for Stroke (ACT-GLOBAL)
Source: ClinicalTrials.gov · Last updated 8 Jul 2026
Brief summary (registry, in English)
Stroke is causing 6.6 million deaths and is a major cause of disability worldwide in 2019. There remains an urgent need for interventions that improve outcomes which can be implemented with wide applicability for stroke. ACT-GLOBAL is a multi-factorial, multi-arm, multi-stage, randomised, global adaptive platform trial for stroke, aiming to identify the treatment/s associated with the highest chance of improving outcome in stroke patients. In ACT-GLOBAL multiple questions will be evaluated simultaneously and sequentially as data accrues and can evaluate interactions between different treatment options.
- Status (registry)
- Recruiting
- Phase (registry)
- Phase 3
- Study type
- Interventional
- Enrollment
- 20000 (estimated)
- First submitted
- 2 Apr 2024
- Start date
- 26 Sept 2024
- Primary completion date
- Sept 2034
- Lead sponsor
- The George Institute
- Diseases
- Stroke
- NCT number
- NCT06352632
What you commit to
- Study type: Interventional · Phase 3
- Planned participants: 20000
- From 26 Sept 2024 to the primary completion date, Sept 2034
- 2 sites in 2 countries
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Criteria the registry did not label
- Platform Inclusion Criteria:
- Age ≥18 years
- Clinical diagnosis of stroke
- Platform Exclusion Criteria:
- There are no platform level exclusion criteria
- Each state and domain will specify additional inclusion and exclusion criteria in the respective Domain-Specific Registration. Patients who fulfill the overall platform criteria will be assessed for enrollment into each active domain.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| The George Institute for Global Health Coordinator of this site? Confirm its status | Sydney | Australia | Recruiting |
| University Of Calgary Coordinator of this site? Confirm its status | Calgary | Canada | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.