NCT06354777Active, not recruiting
REView of ProcEdural FactoRs and Outcomes After Atrial Fibrillation Ablation With Active Esophageal COOLing: A Sub-Study of the REAL AF Registry
Source: ClinicalTrials.gov · Last updated 31 Oct 2025
Brief summary (registry, in English)
This is a multi-center sub-study examining the effectiveness of active esophageal cooling on subjects undergoing left atrial ablation for symptomatic Paroxysmal Atrial Fibrillation or Persistent Atrial Fibrillation.
- Status (registry)
- Active, not recruiting
- Study type
- Observational
- Enrollment
- 312 (actual)
- First submitted
- 28 Feb 2024
- Start date
- Apr 2024
- Primary completion date
- Apr 2026
- Lead sponsor
- Heart Rhythm Clinical and Research Solutions, LLC
- Diseases
- Atrial fibrillation
- NCT number
- NCT06354777
What you commit to
- Study type: Observational
- Participants enrolled: 312
- From Apr 2024 to the primary completion date, Apr 2026
- 6 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Enrolled in an investigational drug or device clinical trial, or any trial that dictates the treatment plan.
Age
- \<18 years of age
Other
- For the purpose of this sub-study, candidates will be excluded if they meet any of the following criteria:
- In the opinion of the investigator, any known contraindication to an ablation procedure.
Who the study is looking for
- Symptomatic Paroxysmal Atrial Fibrillation (AF episode terminate spontaneously within 7 days) or Persistent Atrial Fibrillation (AF sustained beyond 7 days) who, in the opinion of the investigator, are scheduled for ablation for Atrial Fibrillation with active esophageal cooling.
- \>18 years of age
- Index or redo ablation procedure and enrolled in the REAL AF Registry
- Willing and able to provide informed consent and complete GERD questionnaire.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (6)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Valley Heart Rhythm Specialists Coordinator of this site? Confirm its status | Chandler | United States | Unknown status |
| Christ Hospital Coordinator of this site? Confirm its status | Cincinnati | United States | Unknown status |
| Ascension St. Vincent Hospital - Indianapolis Coordinator of this site? Confirm its status | Indianapolis | United States | Unknown status |
| Allegheny General Hospital Coordinator of this site? Confirm its status | Pittsburgh | United States | Unknown status |
| Corewell Health Research Institute Coordinator of this site? Confirm its status | Royal Oak | United States | Unknown status |
| MultiCare Institute for Research & Innovation Coordinator of this site? Confirm its status | Tacoma | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.