NCT06355050Recruiting
Ultrahypofractionated, Adaptive Radiation Therapy of Prostate Cancer
Ultrahypofractionated, Adaptive Radiation Therapy of Prostate Cancer - Ultra-HART
Source: ClinicalTrials.gov · Last updated 11 Jun 2026
Brief summary (registry, in English)
In this prospective, multi-center cohort study, the tolerability and quality of life during ultrahypofractionated radiotherapy (RT) of early stage prostate cancer is surveyed at several institutions in Germany. Radiotherapy is delivered by an online-adaptive RT device (Varian Ethos), which is able to correct daily variations in anatomy and to adjust the irradiation plan accordingly. A digital patient questionnaire is used to asses quality of life longitudinally. Quality of life (QoL) and toxicity profiles will be correlated with planning parameters and compared to retrospective cohorts of patients who underwent normofractionated RT or moderately hypofractionated RT, respectively.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 150 (estimated)
- First submitted
- 27 Mar 2024
- Start date
- 1 Apr 2026
- Primary completion date
- 30 Sept 2027
- Lead sponsor
- Jena University Hospital
- Diseases
- Prostate cancer
- NCT number
- NCT06355050
What you commit to
- Study type: Observational
- Planned participants: 150
- From 1 Apr 2026 to the primary completion date, 30 Sept 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Who the study is looking for
- no androgen deprivation therapy within the last 2 months prior to RT
- good performance status (Eastern Cooperative Oncology Group, ECOG, 0/1)
- no secondary malignancy
Age in the registry: 18 years to 120 years · Sex: Male · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Department of Radiotherapy and Radiation Oncology, Jena University Hospital Coordinator of this site? Confirm its status | Jena | Germany | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.