NCT06365268Completed
Perinatal Thoraco-abdomino-pelvic Tumors Study
Perinatal Thoraco-abdominal Tumors Management in Infants : a Multicenter Experience
Source: ClinicalTrials.gov · Last updated 19 Sept 2025
Brief summary (registry, in English)
Congenital tumors are a rare diagnosis in the fetus and newborn. They differ from those of children and adults in terms of the nature, location and evolution of the tumor. Indeed, some histologically benign tumors may have lethal potential in utero (e.g. sacrococcygeal teratomas) or even undergo malignant transformation if left untreated. In contrast, other tumors that are malignant by histological criteria may have a very good prognosis, regressing spontaneously within the first year of life (e.g. neuroblastoma). Despite advances in imaging, benign and malignant solid tumors remain a major diagnostic and prognostic challenge in the antenatal context. The management of congenital tumors requires multidisciplinary expertise, taking into account the perinatal context, which poses specific problems, particularly in terms of therapeutic aspects, but also the frequent existence of associated malformations and/or genetic predisposition syndromes. This study focuses on solid tumors of the thoraco-abdomino-pelvic region, the main objective being to investigate the correlation between antenatal clinical and radiological analysis and confirmed postnatal diagnosis of congenital solid truncal tumors, as well as the developmental spectrum in which they fit.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 152 (actual)
- First submitted
- 8 Apr 2024
- Start date
- 5 Sept 2024
- Primary completion date
- 10 Oct 2024
- Lead sponsor
- Assistance Publique - Hôpitaux de Paris
- Diseases
- Childhood cancers
- NCT number
- NCT06365268
What you commit to
- Study type: Observational
- Participants enrolled: 152
- From 5 Sept 2024 to the primary completion date, 10 Oct 2024
- 5 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Heart tumors
Other
- Opposition from holders of parental authority of patients
- Sacrococcygeal teratomas
- Central nervous system tumors
- Ovarian cysts
- Head and neck tumors
- Congenital leukemia and hemopathy
Who the study is looking for
- Information of the holders of parental authority of the patients concerned by the research
- Malignant or benign solid tumor
- Thoracic, abdominal or pelvic location
- Clinico-radiological or histological diagnosis confirmed postnatally up to 1 year of life with onset of symptoms in the first three months of life
- Mother-child whose care course for the child's congenital axial tumor included treatment at the AP-HP
Age in the registry: - to 3 months · Sex: All · Does not accept healthy volunteers
Sites (5)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Hopital Antoine Beclere Coordinator of this site? Confirm its status | Clamart | France | Unknown status |
| Hopital Bicetre Coordinator of this site? Confirm its status | Le Kremlin-Bicêtre | France | Unknown status |
| Hopital Necker Enfants Malades Coordinator of this site? Confirm its status | Paris | France | Unknown status |
| Hopital Robert Debre Coordinator of this site? Confirm its status | Paris | France | Unknown status |
| Hôpital Armand-Trousseau Coordinator of this site? Confirm its status | Paris | France | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.