NCT06366399Recruiting
The Acute T-Rex (Timing of Resistance Exercise) Study
Timing (AM v PM) of Acute Resistance Exercise on Glycemic Control in Older Adults: The Acute T-Rex Study
Source: ClinicalTrials.gov · Last updated 3 Apr 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
The primary aim of this study is to evaluate if a single bout of AM vs PM resistance exercise has different effects on insulin sensitivity and sleep. A randomized cross-over trial be used to compare resistance exercise at two different times of the day. Each condition will take place in a laboratory setting. Each condition will consist of exercise, overnight sleep, and oral glucose tolerance tests the following day. The AM exercise will occur \~1.5 hours after habitual wake, and PM exercise will occur \~11 hours after habitual wake. After a 2-6 week washout, participants will complete the other condition. The hypothesis is that PM exercise will be more beneficial than AM exercise in improving insulin sensitivity. This study could identify if there is a better time of day to perform resistance exercise to decrease risk of developing Type 2 Diabetes Mellitus.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 20 (estimated)
- First submitted
- 31 Jan 2024
- Start date
- Nov 2023
- Primary completion date
- Dec 2025
- Lead sponsor
- University of Utah
- Diseases
- Obesity, Type 2 diabetes
- NCT number
- NCT06366399
What you commit to
- Study type: Interventional
- Planned participants: 20
- From Nov 2023 to the primary completion date, Dec 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Current use of weight loss medication or other medications likely to impact energy balance
- Bariatric surgery or extensive bowel resection in the past 2 years
Other illness
- Uncontrolled cardiovascular, metabolic, renal, or pulmonary disease
- Cancer treatment in the past 5 years
- Untreated thyroid disease or other medical conditions affecting weight or energy metabolism
- Current or recent history (past 2 years) of eating disorder
- Diagnosis of insomnia, sleep apnea, or other sleep and circadian disorders
Lab values
- HbA1c \>6.5%
Other
- Non-English speaking
Who the study is looking for
- Men and women, all ethnicities, aged 50-74 years
- BMI ≥25 kg/m² and \<45 kg/m²
- Weight stable (less than 5% change in the past 6 months)
- Generally healthy individuals
- Not meeting recommended activity guidelines for aerobic or resistance exercise
Age in the registry: 50 years to 74 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of Utah HPER E Buildling Coordinator of this site? Confirm its status | Salt Lake City | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.