NCT06367348Recruiting
An Economic and Relationship-strengthening Intervention to Reduce Alcohol Use in Malawi
Mlambe: A Randomized Controlled Trial of an Economic and Relationship-Strengthening Intervention to Reduce Alcohol Use in Malawi
Source: ClinicalTrials.gov · Last updated 14 May 2026
Brief summary (registry, in English)
With a full-scale randomized control trial, the investigators will evaluate the efficacy and cost effectiveness of Mlambe, an economic and relationship-strengthening intervention that provides incentivized saving accounts, financial literacy training, and relationship skills education to break the cycle of poverty around drinking, strengthen couple support and communication, and reduce heavy drinking among HIV-affected married couples with a partner who drinks alcohol in Malawi.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 500 (estimated)
- First submitted
- 10 Apr 2024
- Start date
- 14 Feb 2025
- Primary completion date
- 31 May 2028
- Lead sponsor
- University of California, San Francisco
- Diseases
- HIV
- NCT number
- NCT06367348
What you commit to
- Study type: Interventional
- Planned participants: 500
- From 14 Feb 2025 to the primary completion date, 31 May 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- 1\) Severe intimate partner violence reported in previous 3 months and/or fear that safety would be at risk by participation in the study (reported at screening). Couples who participated in Mlambe's pilot study will also be excluded.
Who the study is looking for
- In a married or cohabitating union
- Have at least one partner with a positive AUDIT-C screen in prior 3 months
- Must also currently be on ART for at least 6 months
- Must have disclosed their HIV status to their partner
Age in the registry: 18 years to - · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Invest in Knowledge Initiative (IKI) Coordinator of this site? Confirm its status | Zomba | Malawi | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.