NCT06374238Recruiting
Peer Support for Adolescents and Emerging Adults With Sickle Cell Pain
Peer Support for Adolescents and Emerging Adults With Sickle Cell Pain: Promoting Engagement in Cognitive Behavioral Therapy
Source: ClinicalTrials.gov · Last updated 8 Oct 2026
Brief summary (registry, in English)
The study, known as the Peer suppoRt for adolescents and Emerging adults with Sickle cell pain: promoting ENgagement in Cognitive behavioral thErapy (PRESENCE), aims to determine the effectiveness of digital CBT in reducing pain, opioid use, and healthcare utilization among AYAs with SCD. It also seeks to understand the role of personalized peer support in enhancing engagement and outcomes of digital CBT interventions. By leveraging existing infrastructure for delivering virtual peer support interventions, tailored digital CBT programs for individuals with SCD, and partnerships with CBOs, the study aims to provide valuable insights into the feasibility and effectiveness of digital CBT as a pain management strategy for this vulnerable population.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 390 (estimated)
- First submitted
- 15 Apr 2024
- Start date
- Mar 2025
- Primary completion date
- Feb 2028
- Lead sponsor
- University of Pittsburgh
- Diseases
- Sickle cell disease
- NCT number
- NCT06374238
What you commit to
- Study type: Interventional
- Planned participants: 390
- From Mar 2025 to the primary completion date, Feb 2028
- 14 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Prior hematopoietic stem cell transplant for sickle cell disease
Other
- Unable to speak or read English
- Not living in the United States throughout enrollment and duration of the study period
Who the study is looking for
- Aged 16 to 39 years of age at time of enrollment
- Sickle Cell Disease diagnosis of any genotype based on referral or documentation
- Reports chronic pain (≥4 days/week for past 3 months or more) OR A) Being prescribed pain medication to be taken (≥4 days/week for past 3 months or more) OR B) Taking pain medication (≥4 days/week for past 3 months or more) OR C) Receiving non-pharmaceutical pain treatment (≥4 days/week for past 3 months or more)
- Access to an iOS or Android mobile device with internet access
Age in the registry: 16 years to 39 years · Sex: All · Does not accept healthy volunteers
Sites (14)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| The Regents of the University of Michigan Coordinator of this site? Confirm its status | Ann Arbor | United States | Recruiting |
| Children's Healthcare of Atlanta Coordinator of this site? Confirm its status | Atlanta | United States | Recruiting |
| Ann and Robert H. Lurie Children's Hospital of Chicago Coordinator of this site? Confirm its status | Chicago | United States | Recruiting |
| Wake Forest Baptist Hospital Coordinator of this site? Confirm its status | Durham | United States | Recruiting |
| East Carolina University Health Medical Center Coordinator of this site? Confirm its status | Greenville | United States | Recruiting |
| Connecticut Children's Medical Center Coordinator of this site? Confirm its status | Hartford | United States | Recruiting |
| UCLA Mattel Children's Hospital Ronald Reagan Hospital Coordinator of this site? Confirm its status | Los Angeles | United States | Recruiting |
| University of South Alabama Medical Center Coordinator of this site? Confirm its status | Mobile | United States | Recruiting |
| Rutgers New Jersey Medical School Coordinator of this site? Confirm its status | Newark | United States | Recruiting |
| Weil Cornell Medical College Coordinator of this site? Confirm its status | New York | United States | Recruiting |
| UPMC Children's Hospital of Pittsburgh Coordinator of this site? Confirm its status | Pittsburgh | United States | Recruiting |
| UPMC University of Pittsburgh Classical Hematology Adult Clinic Coordinator of this site? Confirm its status | Pittsburgh | United States | Recruiting |
| Virginia Commonwealth University Coordinator of this site? Confirm its status | Richmond | United States | Recruiting |
| University of Rochester Medical Center Coordinator of this site? Confirm its status | Rochester | United States | Recruiting |
Related publications
This page is information, not medical advice. Discuss any trial with your doctor.