NCT06375213Recruiting
Investigating Neurocognitive Disorders Epidemiology
Source: ClinicalTrials.gov · Last updated 22 Apr 2024 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
This is a prospective cohort study with the main purpose of predicting progression neurocognitive disorders in Thai population. The main predictor variables to be evaluated are plasma phosphorylated tau (p-tau) level and cognitive test scores, which will be combined using statistical/computational modeling. Additionally, it seeks to evaluate biomarkers for diagnosing disease pathologies, understand their correlation with clinical outcomes, and explore the socioeconomic impact of neurocognitive disorders. The study invites both participants for biospecimen collection, structured interviews, and cognitive examinations and schedules follow-up visits annually or biennially.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 990 (estimated)
- First submitted
- 16 Apr 2024
- Start date
- 24 Aug 2023
- Primary completion date
- 24 Aug 2035
- Lead sponsor
- King Chulalongkorn Memorial Hospital
- Diseases
- Alzheimer disease
- NCT number
- NCT06375213
What you commit to
- Study type: Observational
- Planned participants: 990
- From 24 Aug 2023 to the primary completion date, 24 Aug 2035
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Significant neurological or uncontrolled psychiatric illness.
- Significant unstable systemic condition or end-stage organ failure that affects study participation.
- Mild Cognitive Impairment
- Significant neurological or uncontrolled psychiatric illness.
- Significant unstable systemic condition or end-stage organ failure that affects study participation.
- Late Onset Dementia
- Significant neurological or uncontrolled psychiatric illness.
- Significant unstable systemic condition or end-stage organ failure that affects study participation.
- Early Onset Dementia
- Significant neurological or uncontrolled psychiatric illness.
- Significant unstable systemic condition or end-stage organ failure that affects study participation.
Who the study is looking for
- Demonstrate normal cognitive function within the expected range on objective cognitive tests.
- Proficient in speaking and understanding Thai without the need for a translator to participate.
- Display impaired/abnormal performance on objective cognitive tests.
- Does not meet criteria for dementia per NIA-AA (or major neurocognitive disorder per DSM-5).
- Proficient in speaking and understanding Thai without the need for a translator to participate.
- Display impaired/abnormal performance on objective cognitive tests.
- Meets criteria for dementia per NIA-AA (or major neurocognitive disorder per DSM-5), including dementia due to Alzheimer's disease or other causes.
- Begins to experience symptoms, identified by the physician as a part of dementia continuum, occurring after the age of 65.
- Proficient in speaking and understanding Thai without the need for a translator to participate.
- Display impaired/abnormal performance on objective cognitive tests.
- Meets criteria for dementia per NIA-AA (or major neurocognitive disorder per DSM-5), including dementia due to Alzheimer's disease or other causes.
- Begins to experience symptoms, identified by the physician as a part of dementia continuum, occurring before the age of 65.
- Proficient in speaking and understanding Thai without the need for a translator to participate.
Criteria the registry did not label
- Cognitively Healthy Individuals
Age in the registry: 35 years to - · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| King Chulalongkorn Memorial Hospital Coordinator of this site? Confirm its status | Pathum Wan | Thailand | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.