NCT06376565Recruiting
Improving Colonoscopy Surveillance for Patients With High Risk Colon Polyps
Multilevel Health System Intervention to Increase Guideline-Concordant Surveillance Colonoscopy for High Risk Colon Polyps
Source: ClinicalTrials.gov · Last updated 14 Nov 2025
Brief summary (registry, in English)
This clinical trial tests a multilevel intervention at the clinic, provider and patient levels, to improve colonoscopy surveillance in patients with high risk colon polyps. Colorectal cancer (CRC) is a common and deadly disease that is largely preventable through the detection and removal of colorectal polyps. One million Americans are diagnosed with high risk polyps of the colon or rectum annually and are at increased risk for CRC; however, uptake of recommended repeat colonoscopy in 3 years to reduce CRC risk is low in this group. This multilevel intervention may work to improve timely colonoscopy screening for patients with high risk colon polyps.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 1680 (estimated)
- First submitted
- 10 Apr 2024
- Start date
- Nov 2023
- Primary completion date
- Nov 2027
- Lead sponsor
- Jonsson Comprehensive Cancer Center
- Diseases
- Colorectal cancer
- NCT number
- NCT06376565
What you commit to
- Study type: Interventional
- Planned participants: 1680
- From Nov 2023 to the primary completion date, Nov 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- AIM 2: Individuals with a personal history of colorectal carcinoma (CRC), inflammatory bowel disease (Crohn's, ulcerative colitis), or polyposis syndrome
Other
- AIM 2: HRN cases not confirmed by chart review (human-in-the-loop)
Who the study is looking for
- AIM 1 PATIENTS: Patients between age 45 and 75 with a HRN diagnosis in the past 5 years
- AIM 1 PATIENTS: 12 patients who did and 12 patients who did not have surveillance colonoscopy
- AIM 1 PROVIDERS: Primary care providers (PCPs) and gastroenterologists (GIs)
- AIM 1 ADMINISTRATORS: Administrators who are involved in care processes related to CRC screening, HRN surveillance, and/or colonoscopy scheduling
- AIM 2: Patients age 45 to 75 diagnosed with a HRN during the pre-specified two-year HRN diagnosis period
Age in the registry: 21 years to - · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| UCLA / Jonsson Comprehensive Cancer Center Coordinator of this site? Confirm its status | Los Angeles | United States | Recruiting |
Related publications
- Increasing timely colonoscopy surveillance for patients with high-risk colorectal polyps: Protocol for a cluster randomized trial.Contemp Clin Trials · 2026 · PMID 41260460
This page is information, not medical advice. Discuss any trial with your doctor.