NCT06376669RecruitingPhase 2
Stereotactic Body Proton Therapy for Treatment of Primary Renal Cell Carcinoma
Prospective Phase II Study of Stereotactic Body Proton Therapy for Treatment of PrimAry Renal Cell Carcinoma (SPARE)
Source: ClinicalTrials.gov · Last updated 3 Apr 2026
Brief summary (registry, in English)
This study examines the impact of proton based stereotactic radiation therapy (SBRT) on kidney function as well as other oncologic outcomes including local control, locoregional and systemic failure, progression free and overall survival.
- Status (registry)
- Recruiting
- Phase (registry)
- Phase 2
- Study type
- Interventional
- Enrollment
- 20 (estimated)
- First submitted
- 16 Apr 2024
- Start date
- 25 Feb 2025
- Primary completion date
- Jun 2027
- Lead sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
- Diseases
- Kidney cancer
- NCT number
- NCT06376669
What you commit to
- Study type: Interventional · Phase 2
- Planned participants: 20
- From 25 Feb 2025 to the primary completion date, Jun 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Prior history of radiation treatment with overlapping fields.
Other illness
- Patients with proven metastatic disease.
Other
- Female subjects who are pregnant or planning to become pregnant during the treatment.
Who the study is looking for
- Age ≥ 18 years
- Biopsy proven renal cell carcinoma.
- No clinical or radiographic evidence of metastatic disease.
- Not a candidate for surgical treatment or local ablative procedures.
- Subjects are able to undergo either an MRI or administration of contrast agent for CT.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Sibley Memorial Hospital Coordinator of this site? Confirm its status | Washington D.C. | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.