AN INTERNATIONAL, OBSERVATIONAL, BLINDED STUDY TO ASSESS THE PERFORMANCE OF THE CORDIO HEARO SYSTEM

Criteria the registry did not label

• Major Inclusion Criteria:
• Age 22 or greater
• Diagnosed with Symptomatic Chronic Heart Failure \[NYHA II-IVa (ambulatory)\]
• At least one of the following:
  • One ADHF hospitalization in the last 12 months
  • One unplanned IV/SC diuretic administration in the last 6 months
  • Two unplanned IV/SC diuretic administrations in the last 12 months
  • NTProBNP \>500 pg/ml
• Clinically stable HF according to investigator discretion
• Willing to participate as evidenced by signing the written informed consent.
  • Major Exclusion Criteria:
• Unable to comply with daily use of the App,
• Has had a major cardiovascular event within 3 months prior to enrolment.
• Had a Cardiac Resynchronization Therapy Device (CRT) implanted or upgrading ≤ 1 month prior to screening visit.
• Has estimated Glomerular Filtration Rate (eGFR) \< 30 ml/min/1.73.
• Is likely to undergo heart transplantation/ LVAD within 6 months of Screening Visit.
• Was treated for a significant COPD