NCT06382233Recruiting
The PRO-FUTURE Project
PRecocious biOmarkers oF Unilateral ureTero-pelvic jUnction obstRuction in childrEn
Source: ClinicalTrials.gov · Last updated 30 Apr 2024 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
The goal of this observational study is to learn about specific biomarkers of unilateral ureteropelvic junction obstruction (UPJO) in children undergoing surgical intervention for unilateral UPJO compared with controls. The main question it aims to answer are: * Are Urinary single-cell and extracellular vesicles (EVs) screening useful to stage the intrarenal injury and repair processes in UPJO babies? * Do babies with unilateral UPJO have a whole blood gene expression profiling (WBGEP) allowing an accurate unilateral UPJO diagnosis?
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 85 (estimated)
- First submitted
- 19 Apr 2024
- Start date
- 30 Jan 2024
- Primary completion date
- 30 Jan 2026
- Lead sponsor
- University of Campania Luigi Vanvitelli
- Diseases
- Chronic kidney disease
- NCT number
- NCT06382233
What you commit to
- Study type: Observational
- Planned participants: 85
- From 30 Jan 2024 to the primary completion date, 30 Jan 2026
- 5 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- previous surgical intervention on the urinary tract
Other illness
- urinary tract infections.
Other
- bilateral UPJO
- bladder or lower urinary tract symptoms or malformations
- nephro- or urolithiasis, vesicoureteral reflux
Who the study is looking for
- unilateral UPJO
- 0-5years of age
Age in the registry: 1 day to 5 years · Sex: All · Does not accept healthy volunteers
Sites (5)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico Coordinator of this site? Confirm its status | Milan | Italy | Recruiting |
| Department of Clinical Sciences and Community Health, University of Milano Coordinator of this site? Confirm its status | Milan | Italy | Active, not recruiting |
| Obstetrics and Gynecology Unit, University of Modena and Reggio Emilia Coordinator of this site? Confirm its status | Modena | Italy | Recruiting |
| Aorn Santobono Pausilipon Coordinator of this site? Confirm its status | Naples | Italy | Recruiting |
| Univeristà degli Studi della Campania Luigi Vanvitelli Coordinator of this site? Confirm its status | Naples | Italy | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.