NCT06390189Recruiting
Inflammatory Resolution in Cardiometabolic Health and Disease
Inflammatory Resolution in Cardiometabolic Health and Disease - an Aarhus Based Cohort
Source: ClinicalTrials.gov · Last updated 28 Jun 2024 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
The specific aim of this study is to determine molecular pathways that differentiate metabolically healthy vs unhealthy human phenotypes, and to investigate the therapeutic potential of pro-resolving lipids. Investigators will recruit volunteers that are metabolically healthy or unhealthy that fall within three BMI ranges: lean (18.-24.9 kg/m2), overweight (25.0-29.9 kg/m2) and obese (\>30.0 kg/m2). Investigators hypothesize that metabolically healthy individuals have a superior endogenous capacity to regulate an inflammatory/resolving response.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 240 (estimated)
- First submitted
- 19 Apr 2024
- Start date
- May 2024
- Primary completion date
- Sept 2026
- Lead sponsor
- University of Aarhus
- Diseases
- Obesity
- NCT number
- NCT06390189
What you commit to
- Study type: Observational
- Planned participants: 240
- From May 2024 to the primary completion date, Sept 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- An MD determines that the individual is on too many medications to participate.
- The individual takes a medication that is approved by the MD, but he/she is not willing or not able to wait with any potential morning medication until after their fasted blood-draw.
- The individual regularly uses medication that affects inflammatory resolution (e.g., low-dose aspirin).
- The individual uses immunosuppressive drugs (e.g., methotrexate).
- The individual has been drinking alcohol two days before the study visit.
Other illness
- The individual states that they have increased bleeding tendency or are using anti-coagulant (blood thinning) medication.
Other
- The study staff contacting a potential participant perceives that the individual has difficulty understanding the information.
- The individual has some form of chronic inflammation.
- The individual regularly consumes fish oils (omega 3).
- The individual has significant gastrointestinal problems.
- The individual smokes or uses chewing tobacco.
- The individual has tattoos or body piercings on the forearms and / or the stomach that can affect the examination.
- The individual does not follow instructions given in the research study.
Who the study is looking for
- Informed signed consent has been obtained from the volunteer.
- The volunteer has a BMI greater than 18.5 kg/m2
- Men and women over the age of 18 are included.
Age in the registry: 18 years to 75 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Steno Diabetes Center Aarhus, Aarhus University Hospital Coordinator of this site? Confirm its status | Aarhus | Denmark | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.