NCT06390631Completed
Effect of CPAP on Respiratory Load in COPD
Effect of CPAP on Respiratory Load and Lung Volume in Stable COPD
Source: ClinicalTrials.gov · Last updated 10 Jul 2024
Brief summary (registry, in English)
Both intrinsic positive end expiratory pressure (PEEPi) and dynamic hyperinflation are considered as inspiratory loads which increase work of breathing in patients with COPD. The application of extrinsic positive end expiratory pressure (PEEPe) supplied by CPAP has been claimed to reduce inspiratory load based on change in esophageal pressure which could be significantly affected by change in lung volume and airflow. The investigator hypothesized that CPAP could increase respiratory load because it increases lung volume.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 19 (actual)
- First submitted
- 25 Apr 2024
- Start date
- 1 May 2024
- Primary completion date
- 1 Jul 2024
- Lead sponsor
- State Key Laboratory of Respiratory Disease
- Diseases
- COPD
- NCT number
- NCT06390631
What you commit to
- Study type: Interventional
- Participants enrolled: 19
- From 1 May 2024 to the primary completion date, 1 Jul 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patients with concomitant pulmonary disease (e.g. lung fibrosis, interstitial lung disorder).
Other
- Patients recovering from acute exacerbation less than 4 weeks.
Who the study is looking for
- Willing to participate after informed consent
- Males and females, any race and aged 40-80 years
- GOLD II-IV COPD (post-bronchodilator FEV1 \< 80 % of the predicted normal, and a post-bronchodilator FEV1/FVC \< 0.70)
Age in the registry: 40 years to 80 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Guangzhou Medical University Coordinator of this site? Confirm its status | Guangzhou | China | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.