NCT06394973CompletedPhase 2
Efficacy and Safety Assessment of T4090 Ophthalmic Solution Versus Rhopressa® Ophthalmic Solution in Patients With Open-angle Glaucoma or Ocular Hypertension
Efficacy and Safety Assessment of T4090 Ophthalmic Solution (Preservative-free Kinezodianone R HCl 0.2% or 0.3%) Versus Rhopressa® Ophthalmic Solution (Preserved Netarsudil 0.02%) in Patients With Open-angle Glaucoma or Ocular Hypertension
Source: ClinicalTrials.gov · Last updated 2 Jan 2026
Brief summary (registry, in English)
The main purpose is to compare the ocular hypotensive efficacy and safety of two concentrations of T4090 (Kinezodianone R HCl 0.2% and 0.3%) ophthalmic solution with Rhopressa® ophthalmic solution
- Status (registry)
- Completed
- Phase (registry)
- Phase 2
- Study type
- Interventional
- Enrollment
- 161 (actual)
- First submitted
- 29 Apr 2024
- Start date
- 5 Aug 2024
- Primary completion date
- 21 Nov 2024
- Lead sponsor
- Laboratoires Thea
- Diseases
- Glaucoma, High blood pressure
- NCT number
- NCT06394973
What you commit to
- Study type: Interventional · Phase 2
- Participants enrolled: 161
- From 5 Aug 2024 to the primary completion date, 21 Nov 2024
- 23 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Criteria the registry did not label
- Main Inclusion Criteria:
- Patient (male or female) ≥18 years old
- Patient with Open Angle Glaucoma or Ocular Hypertension in both eyes
- Informed consent dated and signed.
- Main Exclusion Criteria:
- Secondary Open Agle Glaucoma (ex. Pseudoexfoliation, Pigmentary glaucoma)
- Advanced stage of glaucoma
- History of ocular trauma, eye infection, or/and ocular clinically significant inflammation within the 6 previous months.
- Known or suspected hypersensitivity to one of the components of the IMPs or other product used in the clinical study
- Pregnancy (confirmed with a positive urine pregnancy test) or breast-feeding.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (23)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Keystone Research Coordinator of this site? Confirm its status | Austin | United States | Unknown status |
| Glaucoma Associates of Texas Coordinator of this site? Confirm its status | Dallas | United States | Unknown status |
| Segal Drug Trials, Inc Coordinator of this site? Confirm its status | Delray Beach | United States | Unknown status |
| Emerson Clinical Research Institute Coordinator of this site? Confirm its status | Falls Church | United States | Unknown status |
| Global Research Management, Inc Coordinator of this site? Confirm its status | Glendale | United States | Unknown status |
| Arizona Advanced Eye Research Institute Coordinator of this site? Confirm its status | Glendale | United States | Unknown status |
| Seidenberg Protzko Eye Associates Coordinator of this site? Confirm its status | Havre de Grace | United States | Unknown status |
| Houston Eye Associates Coordinator of this site? Confirm its status | Houston | United States | Unknown status |
| United medical research institute Coordinator of this site? Confirm its status | Inglewood | United States | Unknown status |
| East Coast Institute for Research, LLC Coordinator of this site? Confirm its status | Jacksonville | United States | Unknown status |
| Shettle Eye Research, Inc. Coordinator of this site? Confirm its status | Largo | United States | Unknown status |
| Piedmont Eye Center Coordinator of this site? Confirm its status | Lynchburg | United States | Unknown status |
| Total Eye Care, PA Coordinator of this site? Confirm its status | Memphis | United States | Unknown status |
| DCT-Shah Research, LLC sba Discovery Clinical Trials Coordinator of this site? Confirm its status | Mission | United States | Unknown status |
| Mild Florida Eye Center Coordinator of this site? Confirm its status | Mt. Dora | United States | Unknown status |
| Eye Research Foundation Coordinator of this site? Confirm its status | Newport Beach | United States | Unknown status |
| Visionary Research Institute Coordinator of this site? Confirm its status | Newport Beach | United States | Unknown status |
| North Bay Eye Associates Coordinator of this site? Confirm its status | Petaluma | United States | Unknown status |
| Alterman, Modi and Wolter Ophthalmic Surgeons Coordinator of this site? Confirm its status | Poughkeepsie | United States | Unknown status |
| Coastal Research Associates, LLC Coordinator of this site? Confirm its status | Roswell | United States | Unknown status |
| Sacramento Eye Consultants, A Medical Corporation Coordinator of this site? Confirm its status | Sacramento | United States | Unknown status |
| Wolstan and Goldberg Eye Associates Coordinator of this site? Confirm its status | Torrance | United States | Unknown status |
| James D. Branch, MD Coordinator of this site? Confirm its status | Winston-Salem | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.