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NCT06395883Recruiting

Dynamics in Bone Turnover Markers During and After Short-term Glucocorticoid Treatment in Patients With an Inflammatory Joint Disease

Dynamics in Bone Turnover Markers During and After Short-term Glucocorticoid Treatment in Patients With an Inflammatory Joint Disease - the BOOGIE Study

Source: ClinicalTrials.gov · Last updated 19 Aug 2026

Brief summary (registry, in English)

Bone turnover markers (BTMs) are recommended as an important tool in follow-up of osteoporosis treatment. However, there is a lack of knowledge in the reliability of BTMs during and after glucocorticoid treatment. Glucocorticoids suppresses BTMs during treatment with at least 30% and, moreover, glucocorticoids increase the risk of fractures. Patients with an inflammatory joint disease are at increased risk of osteoporosis, and disease flares are often treated with glucocorticoids, which in turn can lead to loss in reliability of the BTMs in patients who also are on osteoporosis treatment. There is a need of more knowledge on BTM changes during and after glucocorticoid treatment for optimized patientcare, reduced risk of side effects and reduced health economic costs.

Status (registry)
Recruiting
Study type
Observational
Enrollment
160 (estimated)
First submitted
29 Apr 2024
Start date
1 Jan 2025
Primary completion date
Oct 2027
Lead sponsor
Diakonhjemmet Hospital
Diseases
Osteoporosis
NCT number
NCT06395883

What you commit to

  • Study type: Observational
  • Planned participants: 160
  • From 1 Jan 2025 to the primary completion date, Oct 2027
  • 2 sites in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • glucocorticoid treatment within the last year prior to inclusion

Other illness

  • active cancer
  • kidney failure

Other

  • known osteoporosis or osteoporosis treatment
  • women during the transitory phase
  • oestrogen treatment
  • any fracture within the last year
  • chronic glucocorticoid treatment

Who the study is looking for

  • diagnosis of inflammatory rheumatic joint disease
  • indication of disease modifying treatment initiation with or without glucocorticoids OR
  • stable DMARD treatment with parenteral glucocorticoid injection

Age in the registry: 25 years to 90 years · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (2)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Vestre Viken HF, Drammen
Coordinator of this site? Confirm its status
DrammenNorwayRecruiting
Diakonhjemmet Hospital
Coordinator of this site? Confirm its status
OsloNorwayRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.