NCT06396260Recruiting
Structural and Functional Networks in ALS: An Insight Into Pseudobulbar Affect
Source: ClinicalTrials.gov · Last updated 29 Jan 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
The investigators aim to elucidate characteristics of structural and functional brain connectivity in patients with amyotrophic lateral sclerosis (ALS) and pseudobulbar affect (PBA) using diffusion kurtosis imaging (DKI) and magnetoencephalography (MEG).
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 50 (estimated)
- First submitted
- 25 Apr 2024
- Start date
- 26 May 2024
- Primary completion date
- 31 Oct 2026
- Lead sponsor
- Aalborg University Hospital
- Diseases
- ALS (motor neurone disease)
- NCT number
- NCT06396260
What you commit to
- Study type: Interventional
- Planned participants: 50
- From 26 May 2024 to the primary completion date, 31 Oct 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Drug addiction defined as the non-prescribed use of cannabis, opioids, or other narcotics.
- Ongoing treatment with any antidepressants or any antipsychotics at recruitment.
Other illness
- Lesional neurological diseases, such as stroke, tumor or multiple sclerosis
- Epilepsy
- Neurodegenerative diseases other than ALS
- Severe psychiatric disease such as major depression disorder, bipolar disease or schizophrenia
- Severe liver or kidney disease
- Dysregulated heart disease
- Diagnosed with frontotemporal dementia.
Other
- \- Lack of ability to answer survey through own ability or through a surrogate, for example by hand controlled, eye-controlled computer and/or tablet, or through telephone interview.
- Lack of ability to cooperate.
- Pregnancy
- Alcohol addiction defined as over 21 units weekly.
- Contraindication for MRI and MEG scan according to hospital guidelines
Who the study is looking for
- Diagnosed with ALS in the last 6 months according to Gold Coast Criteria
Age in the registry: 18 years to 90 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Aalborg University Hospital Coordinator of this site? Confirm its status | Aalborg | Denmark | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.